Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647156 | PMC |
| http://dx.doi.org/10.1016/j.jgar.2021.07.013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Design and Characterization of the Fusion Enzyme of Bovine Terminal Deoxynucleotidyl Transferase and DNA Binding Protein Sso7d from Sulfolobus solfataricus.
Chembiochem
September 2025
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Kuprevich str. 5/2, 220084, Minsk, Belarus.
The terminal deoxynucleotidyl transferase is a unique polymerase that incorporates nucleotides at the 3'-terminus of single-stranded DNA primers in a template-independent manner. This biological function propels the development of numerous biomedical and bioengineering applications. However, the extensive use of TdT is constrained by its low expression levels in E.
View Article and Find Full Text PDFViolacein-Loaded Outer Membrane Vesicles from Exhibit Potent Anti-Melanoma Activity and .
ACS Biomater Sci Eng
September 2025
Departamento de Genética, Evolução, Microbiologia e Immunologia, Instituto de Biologia, Universidade Estadual de Campinas - UNICAMP, Campinas, São Paulo 13083-862, Brazil.
Violacein exhibits antitumor activity, indicating potential for future clinical application. However, an efficient delivery system is required for the clinical use of this hydrophobic compound. Effective delivery systems can enhance the solubility and bioavailability of hydrophobic compounds like violacein, facilitating its clinical application for antitumor therapy.
View Article and Find Full Text PDFImpairment of Regenerative and Metabolic Pathways in Intestinal Organoids From Patients With MASLD-Cirrhosis.
Liver Int
October 2025
Division of Gastroenterology, Acireale Hospital, Azienda Sanitaria Provinciale di Catania, Catania, Italy.
Background And Aims: Gut-liver axis has been implicated in the pathophysiology of cirrhosis due to metabolic dysfunction-associated steatotic liver disease (MASLD), an in vitro model for studying epithelial gut dysfunction in MASLD is lacking. In this study, we aimed to characterise intestinal organoids derived from subjects with MASLD.
Materials And Methods: Intestinal organoids were obtained from duodenal samples of individuals with non-fibrotic MASLD and with MASLD-cirrhosis.
Characterisation of Antifungal Resistance to Azoles in Colombian Isolates of Malassezia spp.
Mycoses
September 2025
Grupo Infección e Inmunidad, Facultad Ciencias de la Salud, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia.
Background: Malassezia genus includes lipodependent commensal yeasts of humans and animals' skin and mucous membranes. It can cause dermatological pathologies, and azoles are mainly used for treatment. However, in vitro susceptibility testing has shown decreased sensitivity to these antifungals.
View Article and Find Full Text PDFEnhanced Energized Dispersive-Guided Extraction Using Doehlert Matrix Optimization and Antioxidant Evaluation of Phenolic Compounds From Herbal Leaves by Using High-Performance Liquid Chromatography.
J Sep Sci
September 2025
Programa De Pós-Graduação em Química, Universidade Federal de Sergipe, São Cristóvão, Sergipe, Brazil.
Secondary metabolites are important bioactive compounds for diet and medicine. This study optimizes the extraction of hydroethanolic herbal extracts using an EDGE (Energized Dispersive Guided Extraction) system, evaluates their antioxidant capacity, and analyzes correlations among antioxidant activity, total phenolic content, and individual compounds. A Doehlert matrix design was used to optimize extraction, having temperature and time as independent variables, and total phenolic content (mg GAE/g) as the response, quantified via the Folin-Ciocalteu method.
View Article and Find Full Text PDF