98%
921
2 minutes
20
Objective: This study aims to evaluate the sensitivity and specificity of the lever sign test in patients with and without chronic Anterior Cruciate Ligament (ACL) injuries in an outpatient setting and the inter-examiner agreement of surgeons with different levels of experience.
Methods: 72 consecutive patients with a history of previous knee sprains were included. The Lachman, anterior drawer, and Lever Sign tests were performed for all subjects in a randomized order by three blinded raters with different levels of experience. Sensitivity, specificity, positive predictive value, negative predictive value, and inter-rater agreement were estimated for all tests.
Results: Among the 72 patients, the prevalence of ACL injuries was 54%. The lever test showed sensitivity of 64.1% (95% CI 0.47-0.78) and specificity of 100% (95% CI 0.87-1.00) for the senior examiner. For the less experienced examiner the sensitivity was 51.8% and the specificity was 93.7%. Positive predictive values (PPV) and negative predictive values (NPV) were 100% and 70.2%, respectively.
Conclusion: Lever Sign test shows to be a maneuver of easy execution, with 100% specificity and 100% PPV. Moderate agreement between experienced examiners and low agreement among experienced and inexperienced examiners was found. This test may play a role as an auxiliary maneuver.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266281 | PMC |
http://dx.doi.org/10.1590/1413-785220212903238345 | DOI Listing |
Proc Natl Acad Sci U S A
July 2025
Department of Ecosystem Science and Sustainability, Colorado State University, Fort Collins, CO 80523.
Salt marshes provide valuable ecosystem services but are vulnerable to drowning with accelerated sea-level rise (SLR). Marsh belowground biomass (BGB) production helps avoid drowning by building marsh surface elevation. Reductions in BGB can serve as an early warning sign of marsh deterioration, as they often precede decreases in aboveground biomass (AGB).
View Article and Find Full Text PDFBehav Processes
August 2025
Washington College, 300 Washington Avenue, Chestertown, MD 21620, USA. Electronic address:
Pavlovian Lever Autoshaping (PLA) is a common method for assessing individual differences in addiction vulnerability, while the Morris water maze (MWM) dual solution task may hold promise as a complimentary behavioral assay. In this procedure, brief lever insertion predicts delivery of a food pellet, non-contingent upon behavior. Sign-trackers preferentially interact with the lever, while goal-trackers preferentially interact with the foodcup.
View Article and Find Full Text PDFOrthop J Sports Med
May 2025
Department of Musculoskeletal and Ageing Science, Institute of Life Course and Medical Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.
Background: Current systematic reviews with meta-analyses have identified the lever sign test as the best clinical examination for ruling out an anterior cruciate ligament (ACL) tear, but the included studies have methodological limitations that could bias the test outcome, potentially overestimating its clinical utility.
Purpose: To investigate the interrater reliability and concurrent validity of the lever sign test after a traumatic knee injury and to investigate the association between test variables (surface used, fist position, effusion grade, force applied, pain reported) and test outcomes.
Study Design: Cohort study (Diagnosis); Level of evidence, 2.
Behav Processes
May 2025
Department of Psychology, Utah State University, United States.
Persistent impulsive choice, preference for a smaller-sooner over a larger-later reward, is associated with consequential life outcomes. Procedures that reduce nonhuman impulsive choice often have long training durations that reduce their translational utility. This experiment sought to alter the behavioral function of the stimulus rats encountered during the delay to the larger-later reward.
View Article and Find Full Text PDFJ Exp Psychol Anim Learn Cogn
April 2025
University of Cardiff, School of Psychology.
Pavlovian conditioning procedures generate spatially and temporally distinct behaviors. For example, after rats have received pairings of a lever with food, they approach the food well during the lever (called goal-tracking) and interact with it (called sign-tracking), with these two spatially distinct behaviors being distributed differently across the temporal duration of the lever. Experiment 1 assessed the development of these spatiotemporally defined behaviors during first-order conditioning, as a function of the sequence in which the lever and food occurred (lever→food or food→lever) and the interval between them (1 s or 11 s).
View Article and Find Full Text PDF