98%
921
2 minutes
20
Two experiments were conducted to determine the effects of feeder design on hay intake, apparent diet digestibility, and hay waste in gestating beef cows. Native tallgrass prairie hay and a protein supplement was fed throughout both experiments. In Exp. 1, 56 crossbred cows were used in a Latin square arrangement. Feeder design treatments included a conventional open bottom steel ring (), an open bottom polyethylene pipe ring (); a sheeted bottom steel ring (), and a sheeted bottom steel ring with a basket (). Cows were weighed and allotted based on BW to one of four previously grazed 2.0 ha paddocks equipped with a concrete feeding pad. Fourteen cows were assigned to each paddock and three round bales were fed consecutively within each treatment period. The cows acclimated to the feeders while the first bale was being consumed. Subsequently, hay waste data were collected while the second and third bale within each period were being consumed. Waste was measured for each bale at 24, 48, 72, and 96 h after each bale was introduced into the pen. Hay waste was significantly affected by hay feeder design with 19.7, 21.1, 12.4, and 5.5% of original bale weight wasted for OBSR, POLY, RING, and BASK, respectively ( < 0.01). There was a feeder design × day interaction ( < 0.01) with greater waste when the bale was first introduced into the pen in OBSR, POLY, and RING feeders and gradually declining thereafter, while waste from the BASK feeder was consistently low. There was a tendency ( = 0.06) for cows eating from OBSR feeders to consume less hay than cows eating from RING feeders. Feeder design did not influence apparent diet digestibility ( = 0.46). In Exp. 2, 64 crossbred cows (body weight = 590 ± 59 kg) were used to determine waste, forage intake, and apparent diet digestibility when hay was fed from a sheeted bottom steel ring () or a RING feeder with a cone insert (). More hay was wasted when cows were fed from RING feeders compared to CONE feeders (11.9% vs. 4.8%, < 0.01). Feeder design had no effect on DMI or apparent digestibility ( > 0.45). Hay savings from adopting a more conservative feeder design can have a dramatic influence on hay utilization by beef cows and thus on cost of production.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281098 | PMC |
http://dx.doi.org/10.1093/tas/txab104 | DOI Listing |
Therapeutic T-cell engineering from human hematopoietic stem cells (HSCs) focuses on recapitulating notch1-signaling and α4β1-integrin-mediated adhesion within the thymic niche with supportive stromal cell feeder-layers or surface-immobilized recombinant protein-based engineered thymic niches (ETNs). The relevant Notch1-DLL-4 and α4β1-integrin-VCAM-1 interactions are known to respond to mechanical forces that regulate their bond dissociation behaviors and downstream signal transduction, yet manipulating the mechanosensitive features of these key receptor-ligand interactions in thymopoiesis has been largely ignored in current ETN designs. Here, we demonstrate that human T-cell development from cord blood-derived CD34 HSCs is regulated via molecular cooperativity in notch1 and integrin-mediated mechanotransduction.
View Article and Find Full Text PDFSensors (Basel)
August 2025
Institute of Transport, Faculty of Mechanical Engineering, VSB-Technical University of Ostrava, 17. listopadu 2172/15, Poruba, 708 00 Ostrava, Czech Republic.
Vibrating feeders are used to empty bulk materials from storage bins, to feed and dispense materials into weighing bins or dispensers, or to feed materials evenly and smoothly into downstream equipment. The harmonic oscillation of the trough can be provided by an electromagnetic oscillator, which consists of an electromagnet consisting of a core and a coil with a given number of coil turns and armature. The aim of this paper has been to verify whether the working condition of the vibrating feeder, i.
View Article and Find Full Text PDFBMC Biotechnol
August 2025
Department of Hematology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Background: Natural killer (NK) cell immunotherapy is a promising approach for cancer treatment. However, its extensive clinical application was limited to the large-scale clinical-grade expansion of NK cells. In this study, we expanded NK cells from healthy donor's peripheral blood mononuclear cells (PBMCs) using a newly designed K562 feeder cell line.
View Article and Find Full Text PDFAnim Biosci
August 2025
North Carolina State University, Raleigh, United States.
Objective: The objective of this study was to investigate the effects of fermented rice bran extract (FRB) with multi-microbial species on intestinal health and growth performance of nursery pigs.
Methods: Thirty weaned pigs (initial body weight = 6.8±0.
Int J Hematol Oncol Stem Cell Res
April 2025
Clinical Immunology Unit, Department of Clinical Pathology, Mansoura Research Centre for Cord Stem Cells (MARC-CSC), Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Umbilical cord blood is widely regarded as a viable option for allogeneic hematopoietic stem cell transplantation (HSCT) and serves as a potential alternative to bone marrow due to its numerous advantages. These include a non-invasive collection process, a high concentration of hematopoietic stem and progenitor cells, and a lower risk of graft rejection. However, its application in adult patients is limited by the suboptimal dose of stem cells available in a single umbilical cord blood unit.
View Article and Find Full Text PDF