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The ability to produce force is critical to several daily activities. Strategies to reduce delayed onsent muscle soreness (DOMS) and restore force-generating properties that occur in response to training and impair physical performance have been proposed. Acupuncture has been proposed to accelerate recovery and optimize muscle functioning. It was to determine the effects of acupuncture on DOMS and on the muscle force production capacity. Thirty physically active volunteers (26.3 ± 3.1 years old, 1.70 ± 0.08 m, 66.5 ± 12.6 kg) were allocated in a control (CG; = 10), placebo (PG; = 10), and acupuncture (AG; = 10) groups. The groups were subjected to an exercise protocol to induce DOMS and were assessed for muscle force, threshold, and rate of perceived pain and activation of the biceps brachialis muscle before (PRE) and 20 minutes after (POST) a single acupuncture session using a mixed model analysis. : The threshold and rate of perceived pain were reduced in the AG ( < 0.05) but remained unchanged in the other groups ( > 0.05). Muscle activation also showed larger changes in the AG in comparison with the other groups ( < 0.05). No changes in the ability to produce force were found after acupuncture in any groups ( > 0.05). Acupuncture may reduce discomfort and improve muscle activation but was not effective to promote force improvement and/or restore the force-generating properties. It may be speculated that muscle disruption may have played a role and did not allow participants to restore their muscular performance. Rebec Number; RBR-8bh5k7 (www.ensaiosclinicos.gov.br/rg/RBR-8bh5k7); Clinical Trial Registry (UTN No.: U1111-1234-9553).
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http://dx.doi.org/10.1089/acu.2020.1491 | DOI Listing |
Trop Doct
September 2025
Fellow in Pediatric Critical Care, Department of Pediatrics, Bharati Vidyapeeth (Deemed to be University), Pune, MH, India.
Tetanus is a rapidly progressive, life-threatening illness with the clinical hallmark of muscle spasms associated with respiratory and neurological sequelae, especially in the unimmunised population. Non-neonatal tetanus continues to be a rare diagnosis. We hereby report six cases admitted to our intensive care unit, highlighting the varied clinical features, management strategies and outcomes.
View Article and Find Full Text PDFJ Neurophysiol
September 2025
Graduate School of Science and Technology, Shinshu University, 3-15-1 Tokida, Ueda, Nagano 3868567, Japan.
This study investigated the correlation between the strength of correlated effective neural drive (END) to the antagonistic muscles and the fluctuations in neural/electrical and mechanical output around the joint during steady co-contraction, and whether the correlated END strength estimated from conventional surface EMG is correlated with that determined from motor unit (MU) discharges. Fourteen young male participants performed isometric steady co-contractions with their medial gastrocnemius and tibialis anterior muscles at 10% of maximal EMG while sitting. Correlated END strength was quantified as the maximum value of the cross-correlation function between the conventional surface EMG signals and between MU discharges decomposed from high-density surface EMG of each muscle.
View Article and Find Full Text PDFPLoS One
September 2025
Biobank of Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu, PR China.
Heart failure (HF) and lung cancer (LC) often coexist, yet their shared molecular mechanisms are unclear. We analyzed transcriptome data from the NCBI Gene Expression Omnibus (GEO) database (GSE141910, GSE57338) to identify 346 HF‑related differentially expressed genes (DEGs), then combined weighted gene co-expression network analysis (WGCNA) pinpointed 70 hub candidates. Further screening of these 70 hub candidates in TCGA lung cancer cohorts via LASSO, Random Forest, and multivariate Cox regression suggested CYP4B1 as the only independent prognostic marker.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.
Objective: This study investigates the mechanisms behind exercise capacity in adults with type 2 diabetes mellitus (T2DM), focusing on central and peripheral components, as described by the Fick equation.
Methods: A cross-sectional study of 141 adults with T2DM was conducted, using cardiopulmonary exercise testing, near-infrared spectroscopy (NIRS) and exercise echocardiography. Participants with sufficient-quality NIRS data were stratified into tertiles based on percentage predicted VO₂peak.