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The field of infancy research faces a difficult challenge: some questions require samples that are simply too large for any one lab to recruit and test. ManyBabies aims to address this problem by forming large-scale collaborations on key theoretical questions in developmental science, while promoting the uptake of Open Science practices. Here, we look back on the first project completed under the ManyBabies umbrella - ManyBabies 1 - which tested the development of infant-directed speech preference. Our goal is to share the lessons learned over the course of the project and to articulate our vision for the role of large-scale collaborations in the field. First, we consider the decisions made in scaling up experimental research for a collaboration involving 100+ researchers and 70+ labs. Next, we discuss successes and challenges over the course of the project, including: protocol design and implementation, data analysis, organizational structures and collaborative workflows, securing funding, and encouraging broad participation in the project. Finally, we discuss the benefits we see both in ongoing ManyBabies projects and in future large-scale collaborations in general, with a particular eye towards developing best practices and increasing growth and diversity in infancy research and psychological science in general. Throughout the paper, we include first-hand narrative experiences, in order to illustrate the perspectives of researchers playing different roles within the project. While this project focused on the unique challenges of infant research, many of the insights we gained can be applied to large-scale collaborations across the broader field of psychology.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244655 | PMC |
http://dx.doi.org/10.1037/cap0000216 | DOI Listing |
Cereb Cortex
August 2025
Section of Brain Function Information, National Institute for Physiological Sciences, 38 Nishigonaka, Myodaiji, Okazaki, Aichi 444-8585, Japan.
This study aimed to identify brain activity modulations associated with different types of visual tracking using advanced functional magnetic resonance imaging techniques developed by the Human Connectome Project (HCP) consortium. Magnetic resonance imaging data were collected from 27 healthy volunteers using a 3-T scanner. During a single run, participants either fixated on a stationary visual target (fixation block) or tracked a smoothly moving or jumping target (smooth or saccadic tracking blocks), alternating across blocks.
View Article and Find Full Text PDFDiabetologia
September 2025
Department of Diabetology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.
This review article, developed by the EASD Global Council, addresses the growing global challenges in diabetes research and care, highlighting the rising prevalence of diabetes, the increasing complexity of its management and the need for a coordinated international response. With regard to research, disparities in funding and infrastructure between high-income countries and low- and middle-income countries (LMICs) are discussed. The under-representation of LMIC populations in clinical trials, challenges in conducting large-scale research projects, and the ethical and legal complexities of artificial intelligence integration are also considered as specific issues.
View Article and Find Full Text PDFFront Genet
August 2025
Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Background And Objective: Parental chromosomal structural variations (SVs) represent a primary genetic factor contributing to recurrent spontaneous abortion (RSA). Individuals carrying SVs with complex chromosomal rearrangements (CCRs) typically exhibit a normal phenotype but are at an increased risk of miscarriage. Current standard clinical detection methods are insufficient for the identification and interpretation of all SV types, particularly complex and occult SVs, thereby presenting a significant challenge for clinical genetic counseling.
View Article and Find Full Text PDFEnviron Res
September 2025
Thrust of Sustainable Energy and Environment, Function Hub, The Hong Kong University of Science and Technology (Guangzhou), Guangzhou 510000, China. Electronic address:
China's aluminum-products industry, a large-scale consumer of industrial paints, is a potentially significant source of full-volatility organic compounds (F-VOCs). However, the emission characteristics of F-VOCs, including VOCs, intermediate-, semi-, and low-volatility organic compounds (I/S/LVOCs), and their role in ozone formation potentials (OFP), and secondary organic aerosol formation potentials (SOAP) remain unclear. In this study, we collected in-field samples from three industrial paints (solvent-based, water-based and powder paints) at spraying and drying processes, and treatment devices to analyze the emission characteristics of F-VOCs, OFP, SOAP.
View Article and Find Full Text PDFEnviron Res
September 2025
School of Ecology and Environment, Anhui Normal University, Wuhu 241002, P. R. China; State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Jiangsu, 210023, P.R. China. Electronic address:
Trivalent antimony (Sb(III)) is listed as a priority aquatic contaminant due to its high toxicity. The oxidation of Sb(III) to pentavalent antimony (Sb(V)) and recovery is a desirable process for treatment of Sb-containing wastewater. Given the challenges of low cost and green production, researches on constructing an oxidation route in the absence of homogeneous oxidant for Sb oxidation and recovery are urgent.
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