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Article Abstract
Encapsulated bacteria such as , type b and cause significant morbidity and mortality in young children despite the availability of vaccines. Highly specific antibodies are the primary mechanism of protection against invasive disease. Robust and standardised assays that measure functional antibodies are also necessary for vaccine evaluation and allow for the accurate comparison of data between clinical studies. This mini review describes the current state of functional antibody assays and their importance in measuring protective immunity.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234458 | PMC |
| http://dx.doi.org/10.3390/vaccines9060677 | DOI Listing |
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