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() is associated with urethritis, cervicitis, pelvic inflammatory disease, proctitis and epididymitis. Its treatment is complicated by antimicrobial resistance. To assess clinicians' adherence to diagnostic testing recommendations for syndromic presentations, as well as resistance-guided management of at Sydney Sexual Health Centre, we reviewed patients presenting between August and December 2018. 349/372 (94%) syndromic presentations were tested for with 16% test positivity and 81% macrolide resistance. 16/27 (59%) macrolide-sensitive infections and 65/77 (84%) macrolide-resistant infections received resistance-guided treatment. Tests of cure (TOCs) were unnecessarily ordered for 82% macrolide-sensitive cases, while 88% macrolide-resistant cases were correctly ordered TOCs. Co-existing STIs at the time of macrolide-sensitive ( = 0.30) or macrolide-resistant ( = 0.94) diagnosis did not significantly affect adherence to treatment guidelines. This study confirms the expected prevalence of and macrolide resistance in syndromic presentations while our real-world data highlight the decision-making challenges involved with managing , offering insights for further research.
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http://dx.doi.org/10.1177/09564624211022583 | DOI Listing |
Ther Adv Respir Dis
September 2025
Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Background: Hermansky-Pudlak syndrome (HPS) is a rare disease characterized by excessive bleeding, oculocutaneous albinism, and pulmonary fibrosis (PF). However, few studies have systematically summarized the clinical characteristics of HPS.
Objectives: To summarize the clinical characteristics, risk factors of PF, radiological and pathological presentations, and prognostic factors in patients with HPS.
Clinics (Sao Paulo)
September 2025
Department of Physiotherapy, Speech Therapy and Occupational Therapy, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
Introduction: The association between Fibromyalgia (FM) and the FMR1 gene premutation has been suggested, but remains inconclusively established. Previous studies often focus on whether women with FM have the FMR1 premutation, while a more appropriate approach would involve examining FM manifestation in women with the premutation. FM is a condition with multifactorial etiology, and while the rarity of the FMR1 premutation makes it unlikely that most FM cases are linked to this variation, an increased prevalence of FM among premutation carriers is still plausible.
View Article and Find Full Text PDFSemin Dial
September 2025
Department of Nephrology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Background: In hyponatremic patients, concurrent dialysate flow during hemodialysis may be an ideal option to mitigate complications such as osmotic demyelination syndrome (ODS).
Methods: Present randomized controlled trial enrolled dialysis-requiring chronic kidney disease (CKD) and acute kidney injury (AKI) patients with serum sodium levels < 125 mEq/L during January 2020 over 16 months. Hemodynamically unstable patients, as well as those with a history of seizures and neurological conditions, were excluded.
J Prof Nurs
September 2025
Department of Applied Social Sciences, Technological University of the Shannon Midlands Midwest, Limerick, Ireland. Electronic address:
Effective scholarly writing is essential for academic success, yet it often presents challenges, including feelings of isolation and imposter syndrome. These challenges can lead to avoidance and procrastination, impeding progress in graduate studies and publications. In response to these common struggles, a virtual writing community called TUS WEWRITE! was piloted for twenty master's and PhD students and research-active faculty and administrative staff at the Technological University of the Shannon (TUS) Midlands Midwest in Ireland.
View Article and Find Full Text PDFJ Microbiol Methods
September 2025
French Armed Forces Medical Directorate, Veterinary Quality Unit, Paris, France.
Foodborne diseases are caused by various pathogens and generally present with similar symptoms, mainly digestive disorders. Adopting a syndromic approach is therefore important when investigating foodborne disease outbreaks. This involves using multiplex PCR-based methods to test stool and food samples.
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