Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164336 | PMC |
| http://dx.doi.org/10.1016/j.jdin.2021.05.005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Social determinants of health, quality of life, and productivity outcomes among adults with vitiligo in Brazil, China, India, and South Africa.
J Dermatolog Treat
December 2025
Pfizer Inc, New York, NY, USA.
Objectives: Vitiligo is an autoimmune disease resulting in skin depigmentation and individuals report substantial psychosocial burden. However, vitiligo-related quality of life impacts appear heterogeneous and may be influenced by social determinants of health. This cross-sectional survey aimed to describe characteristics and vitiligo-related quality of life impacts among adults in Brazil, China, India, and South Africa.
View Article and Find Full Text PDFScalable Acid-Aided Lysis of Skin Samples Improves Proteome Coverage.
J Invest Dermatol
September 2025
LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, DK. Electronic address:
Liquid chromatography-mass spectrometry (LC-MS) is an evolving tool for comprehensive proteomic analyses across tissues. Despite the widespread use of LC-MS in dermatology, full-thickness human skin remains challenging to analyse. The skin extracellular matrix (ECM) presents two major obstacles: the extensive crosslinking complicates protein extraction and the high abundance of ECM proteins can mask lower-abundance proteins, reducing identification numbers.
View Article and Find Full Text PDFRocatinlimab: A Novel T-Cell Rebalancing Therapy Targeting the OX40 Receptor in Atopic Dermatitis.
Dermatol Ther (Heidelb)
September 2025
Department of Dermatology, Kyoto University, Kyoto, Japan.
Atopic dermatitis (AD) is a chronic inflammatory disease characterized by eczematous skin lesions, intense pruritus, skin pain, sleep disruption, and mental health disturbances. There remains a need for a therapeutic option that delivers durable efficacy, safety, and convenient dosing across the AD patient population. This review provides an overview of AD pathogenesis driven by T-cell imbalance and describes a novel therapeutic option targeting the OX40 receptor, a costimulatory molecule expressed specifically on activated T cells.
View Article and Find Full Text PDFSystemic infection of Prohemistomum vivax and Cyanodiplostomum encysted metacercariae in African catfish (Clarias gariepinus) from a heavily polluted drain at Giza, Egypt: morphological, molecular and histopathological study.
Parasitol Int
September 2025
Department of Aquatic Animal Medicine and Management, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.
Aquatic environmental pollution could be a direct trigger of infection through cercarial invasion to skin / gills or indirectly as a predisposing factor that damage the physical barriers of targeted fish resulting in high intensities of EMC infections in all fish vital organs. In the current study, a total of 150 African catfish (Clarias gariepinus) were randomly collected from Mariotteya drain all the way through the Egyptian township of Shabramant located at the historical heart of Giza. Catfish samples were collected in mid-summer during the period from June to July 2024.
View Article and Find Full Text PDFBackground: Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder characterized by complex interactions among Staphylococcus aureus colonization and immunologic, genetic, and environmental (SAIGE) triggers. Currently, no single therapy comprehensively addresses all triggers and the full spectrum of AD manifestations, highlighting an unmet need for therapies that simultaneously target all components of the disease continuum.
Methods: An expert panel conducted a structured literature review and developed consensus statements during a meeting in March 2025.