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Article Abstract
Cationic glycopolymers with structures similar to those of typical poly(ionic liquid)s (PILs) were synthesized the quaternization reaction of poly(4-vinyl pyridine) with halogen-functionalized d-mannose and tetraphenylethylene units. Such postpolymerization modification provided PILs with aggregation-induced emission effect as well as specific carbohydrate-protein recognition with lectins such as concanavalin A. The interactions between cationic glycopolymers and different microorganisms, including Gram-positive and Gram-negative , were used for the killing, imaging, and detection of bacteria. Besides, these sugar-containing PILs showed a relatively low hemolysis rate due to the presence of saccharide units, which may have potential application in the field of biomaterials.
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| http://dx.doi.org/10.1021/acs.biomac.1c00298 | DOI Listing |
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