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The role of accommodation in myopia development and progression has been debated for decades. More recently, the understanding of the mechanisms involved in accommodation and the consequent alterations in ocular parameters has expanded. This International Myopia Institute white paper reviews the variations in ocular parameters that occur with accommodation and the mechanisms involved in accommodation and myopia development and progression. Convergence is synergistically linked with accommodation and the impact of this on myopia has also been critiqued. Specific topics reviewed included accommodation and myopia, role of spatial frequency, and contrast of the task of objects in the near environment, color cues to accommodation, lag of accommodation, accommodative-convergence ratio, and near phoria status. Aspects of retinal blur from the lag of accommodation, the impact of spatial frequency at near and a short working distance may all be implicated in myopia development and progression. The response of the ciliary body and its links with changes in the choroid remain to be explored. Further research is critical to understanding the factors underlying accommodative and binocular mechanisms for myopia development and its progression and to guide recommendations for targeted interventions to slow myopia progression.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083074 | PMC |
http://dx.doi.org/10.1167/iovs.62.5.4 | DOI Listing |
Zhonghua Yan Ke Za Zhi
September 2025
Beijing Tongren Eye Center, Beijing Institute of Ophthalmology, Beijing Ophthalmology&Visual Sciences Key Lab, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
Pathological myopia is one of the primary causes of irreversible visual loss in the population. Myopic maculopathy represents a key feature of pathological myopia, among which macular atrophy is the main contributor to severe visual impairment. The specific mechanism underlying the development of macular atrophy remains unclear.
View Article and Find Full Text PDFAm J Ophthalmol
September 2025
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; Duke-NUS Graduate Medical School, Singapore; Department of Ophthalmology, Emory University School of Medicine, Emory University; Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta
Purpose: To characterize the 3D structural phenotypes of the optic nerve head (ONH) in patients with glaucoma, high myopia, and concurrent high myopia and glaucoma, and to evaluate their variations across these conditions.
Design: Retrospective cross-sectional study.
Participants: A total of 685 optical coherence tomography (OCT) scans from 754 subjects of Singapore-Chinese ethnicity, including 256 healthy (H), 94 highly myopic (HM), 227 glaucomatous (G), and 108 highly myopic with glaucoma (HMG) cases METHODS: We segmented the retinal and connective tissue layers from OCT volumes and their boundary edges were converted into 3D point clouds.
Vestn Oftalmol
September 2025
Northern State Medical University, Arkhangelsk, Russia.
Unlabelled: The diagnostic potential of computer accommodography remains insufficiently studied. At the same time, accommodative and refractive disorders are extremely common today among the youth.
Objective: This study investigated objective accommodative parameters using computer accommodography in samples of individuals aged 17-19 and 20-23 years with and without a diagnosis of myopia.
Transl Vis Sci Technol
September 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, People's Republic of China.
Purpose: The purpose of this study was to estimate the correlations between macular optical coherence tomography (OCT)-derived metrics and incident glaucoma risk in myopic eyes.
Methods: This longitudinal observational study included 24,181 individuals with myopia (spherical equivalence [SE] ≤ -0.5 diopters [D]) from the UK Biobank study.
Clin Ophthalmol
August 2025
Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu City, Sichuan Province, People's Republic of China.
Purpose: To evaluate the efficacy, safety, and predictability of Keratorefractive Lenticule Extraction (KLEx) surgery guided by a VISULYZE-generated nomogram for myopia and astigmatism correction.
Methods: This prospective cohort study included 130 consecutive patients (260 eyes) undergoing KLEx surgery using a VISULYZE-generated nomogram. Patients were followed for 3 months postoperatively.