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Facial expression transfer between two unpaired images is a challenging problem, as fine-grained expression is typically tangled with other facial attributes. Most existing methods treat expression transfer as an application of expression manipulation, and use predicted global expression, landmarks or action units (AUs) as a guidance. However, the prediction may be inaccurate, which limits the performance of transferring fine-grained expression. Instead of using an intermediate estimated guidance, we propose to explicitly transfer facial expression by directly mapping two unpaired input images to two synthesized images with swapped expressions. Specifically, considering AUs semantically describe fine-grained expression details, we propose a novel multi-class adversarial training method to disentangle input images into two types of fine-grained representations: AU-related feature and AU-free feature. Then, we can synthesize new images with preserved identities and swapped expressions by combining AU-free features with swapped AU-related features. Moreover, to obtain reliable expression transfer results of the unpaired input, we introduce a swap consistency loss to make the synthesized images and self-reconstructed images indistinguishable. Extensive experiments show that our approach outperforms the state-of-the-art expression manipulation methods for transferring fine-grained expressions while preserving other attributes including identity and pose.
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http://dx.doi.org/10.1109/TIP.2021.3073857 | DOI Listing |
BMC Nurs
September 2025
International Islamic Center for Population Studies and Research, Al-Azhar University, Cairo, Egypt.
Background: Postgraduate education is embracing journal clubs (JCs), which provide a platform for members to critically evaluate research articles and extract evidence-based nursing practice. The implementation of JCs by postgraduate nurses, especially in varied educational contexts such as Egypt, remains underexplored. This study aimed to explore and gain valuable insights into the professional experiences of implementing JCs among postgraduate nursing students in Egypt.
View Article and Find Full Text PDFPharm Res
September 2025
Mechanical and Aerospace Engineering Department, University of Texas at Arlington, 500 W First St, Rm 211, Arlington, TX, 76019, USA.
Objective: A fundamental understanding of drug diffusion and binding processes is critical for the design and optimization of a wide variety of drug delivery devices. Most of the past literature assume binding to occur uniformly throughout the tissue, or, at best, in specific layers of a multilayer tissue. However, in many realistic scenarios, such as in cancer-targeting drugs, drug binding occurs in discrete irregularly shaped regions.
View Article and Find Full Text PDFChem Biol Interact
September 2025
Department of Systems Medicine. School of Medicine. University of Dundee, Ninewells Hospital, Dundee, DD1 9SY, UK.
Humans are exposed to mixtures of chemical pollutants from various environmental sources at all stages of life. Understanding how these compounds are causally linked to population health effects is challenging because of the ethical limitations on studying controlled human exposures and the complexity of the many potential molecular mechanisms involved. We hypothesized that studies using a combination of in vivo murine stress reporter models together with non-targeted global transcriptome analysis will define the toxic mechanisms of complex chemical mixtures in a physiological context.
View Article and Find Full Text PDFInsect Biochem Mol Biol
September 2025
State Key Laboratory of Biocontrol, School of Ecology, Sun Yat-sen University, Shenzhen, China. Electronic address:
Horizontal gene transfer (HGT) is now widely recognized as an important mechanism contributing to host immunity and adaptation. Ladybird beetles, with their diverse diets and habitats, encounter a broad spectrum of microbial threats, making effective immune responses critical for their survival. However, the immune roles of HGT-acquired genes in ladybirds remain largely unexplored.
View Article and Find Full Text PDFmBio
September 2025
APC Microbiome Ireland, Biosciences Institute, Biosciences Research Institute, University College, Cork, Ireland.
Bacteriocins are antimicrobial peptides/proteins that can have narrow or broad inhibitory spectra and remarkable potency against clinically relevant pathogens. One such bacteriocin that is extensively used in the food industry and with potential for biotherapeutic application is the post-translationally modified peptide, nisin. Recent studies have shown the impact of nisin on the gastrointestinal microbiome, but relatively little is known of how abundant nisin production is in nature, the breadth of existing variants, and their antimicrobial potency.
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