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Global emergence of vector-borne and zoonotic diseases presents a rapidly growing 'wicked' problem. We outline the need for a transdisciplinary research program that is grounded in ecological and evolutionary theory but integrates fundamentally with research perspectives spanning the health, social, and natural sciences.
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http://dx.doi.org/10.1016/j.pt.2021.03.008 | DOI Listing |
Phys Rev Lett
August 2025
Purdue University, Department of Physics and Astronomy, West Lafayette, Indiana 47907, USA.
We experimentally and numerically study the collapse dynamics of a quantum vortex in a two-dimensional atomic superfluid following a fast interaction ramp from repulsion to attraction. We find the conditions and timescales for a superfluid vortex to radially converge into a quasistationary density profile, demonstrating the spontaneous formation of a vortex solitonlike structure in an atomic Bose gas. We record an emergent self-similar dynamics caused by an azimuthal modulational instability, which amplifies initial density perturbations and leads to the eventual splitting of a solitonic ring profile or direct fragmentation of a superfluid into disordered, but roughly circular arrays of Townes solitonlike wave packets.
View Article and Find Full Text PDFJ Speech Lang Hear Res
September 2025
Department of Speech and Hearing Science, The Ohio State University, Columbus.
Purpose: Linguistic entrainment (i.e., increasing linguistic similarity over time) and its positive social effects are well documented among non-autistic communicators.
View Article and Find Full Text PDFMol Divers
September 2025
Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, 11942, Al Kharj, Saudi Arabia.
Cyclin-dependent kinase 20 (CDK20), also known as cell cycle-related kinase (CCRK), plays a pivotal role in hepatocellular carcinoma (HCC) progression by regulating β-catenin signaling and promoting uncontrolled proliferation. Despite its emerging significance, selective small-molecule inhibitors of CDK20 remain unexplored. In this study, a known CDK20 inhibitor, ISM042-2-048, was employed as a reference to retrieve structurally similar compounds from the PubChem database using an 85% similarity threshold.
View Article and Find Full Text PDFInfect Drug Resist
September 2025
Department of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, Jilin, 130000, People's Republic of China.
In recent years, reports of hypervirulent (hv) carbapenem-resistant (CR) (Kp) (hv-CRKp) have gradually increased. hv-CRKp may emerge from hvKp acquiring mobile genetic elements carrying multiple antibiotic-resistance genes or multi-drug-resistant Kp acquiring virulence genes, with subsequent convergence of resistance and virulence. Thus, hv-CRKp simultaneously harbors resistance and virulence genes and may even show resistance to colistin and tigecycline, suggesting potential for causing severe infections and placing a serious burden on the health care system.
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