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The aim of our study was to determine whether patients with neutropenia (absolute neutrophil count (ANC) ≤1,500 cells/µL) had higher rates of surgical site infection after elective abdominal wall reconstruction. This was a case series from a prospective complex abdominal wall reconstruction cohort describing the surgical outcomes of 4 neutropenic patients (ANC ≤1,500 cells/µL) within 48 hours of index operation. Median age was 55 years, 3 patients were female. All patients had liver cirrhosis as a comorbidity: 2 patients as a result of alcohol abuse and 2 patients secondary to cryptogenic and nonalcoholic fatty liver disease, respectively. All patients underwent a posterior component separation with transversus abdominis release and retro-rectus biologic mesh. None of the 4 patients developed a surgical site infection 90 days postoperatively. Complex abdominal wall reconstruction in neutropenic patients could be safe.
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http://dx.doi.org/10.1177/00031348211011086 | DOI Listing |
Forensic Sci Int
August 2025
Department of Laboratory Medicine and Pathobiology, University of Toronto, Canada.
We report the forensic and clinicopathological spectrum of 14 postmortem cases involving the vertebral artery. In all cases, there was either pontocerebellar infarction (n = 8) or subarachnoid hemorrhage (n = 6). The underlying pathology of the vertebral artery was segmental mediolytic arteriopathy (n = 5), traumatic rupture of the arterial wall (n = 3), arterial dissection (n = 2), or atherosclerosis (n = 4).
View Article and Find Full Text PDFCarbohydr Polym
November 2025
State Key Laboratory of Advanced Fiber Materials (Donghua University), Shanghai 201620, China; College of Biological Science and Medical Engineering, Donghua University, No. 2999 North Renmin Road, Shanghai 201620, China; Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Med
Small-caliber artificial blood vessels are highly demanded and face challenges, including thrombosis and intimal hyperplasia. The excellent properties of bacterial nanocellulose (BNC) make it an excellent material for preparing artificial blood vessels. Heparin (Hep)-loaded silk fibroin microparticles (SFMPs) were synthesized in situ within the conduit wall via liquid pressure injection and phase separation, aiming to improve BNC's anticoagulant properties.
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September 2025
Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Introduction: Blue light (peak wavelength 442 nm) has been shown to modulate the immune response in preclinical models of intra-abdominal sepsis and pneumonia. pathways involve optic nerve stimulation with transmission to the central nervous system, activation of parasympathetic pathways terminating at the spleen, and downstream immune effects including decreased inflammatory tissue damage and improved pathogen clearance. Related effects on pain mediators including proinflammatory cytokines (interleukin 6, TNF- α) and autonomic tone (increased parasympathetic outflow) suggest possible analgesic properties that would be highly relevant to a trauma population.
View Article and Find Full Text PDFInt J Surg Case Rep
September 2025
Department of General Surgery A21, Charles Nicolle University Hospital, Faculty of Medicine of Tunis, Tunisia.
Introduction And Importance: Foreign body ingestion is a significant clinical concern, particularly among elderly and psychiatric patients, often leading to complications such as intestinal obstruction. In this article, we present an intriguing case of dual intestinal and urinary obstruction caused by the ingestion of a dental bridge in a patient with Bricker urinary diversion. Through this rare case, we aim to explore the diagnostic and therapeutic challenges associated with such incidents, supported by a comprehensive review of the literature.
View Article and Find Full Text PDFInt J Surg Case Rep
September 2025
Department of Surgery, College of Health Science, Salale University, Fiche, Ethiopia. Electronic address:
Introduction And Importance: Perforated peptic ulcer disease (PUD) represents a serious complication of PUD. Its association with pneumatosis intestinalis (PI) is exceedingly rare. PI is identified by the presence of gas within the bowel wall.
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