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http://dx.doi.org/10.1001/jama.2021.0827 | DOI Listing |
J Lipid Res
September 2025
Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada, M5S 1A8. Electronic address:
Young females have higher circulating docosahexaenoic acid (DHA) levels than males, though the metabolic basis remains incompletely understood. Building on previous findings demonstrating higher hepatic synthesis of the DHA precursor, docosapentaenoic acid (DPAn-3) in males, this study extends the investigation to n-3 PUFA turnover in extrahepatic tissues of male and female C57BL/6N mice using compound-specific isotope analysis (CSIA). Animals were fed a 12-week diet enriched in either α-linolenic acid (ALA), eicosapentaenoic acid (EPA), or DHA, starting with a 4-week phase containing low carbon-13 (δC)-n-3 PUFA, followed by an 8-week phase with high δC-n-3 PUFA (n = 4 per diet, time point, sex).
View Article and Find Full Text PDFFood Sci Nutr
September 2025
Fats and Oils Department, Food Industries and Nutrition Research Institute National Research Centre Cairo Egypt.
This study developed a vegan chocolate spread using spray-dried plant-based milk powders (soy, lentil, and rice), fortified with nano-liposomal vitamin D3 and an oleogel-balanced omega fatty acid to enhance nutritional quality. The plant-based milk powders exhibited high protein (up to 26.8% in soy), fiber, and micronutrients.
View Article and Find Full Text PDFJ Anim Sci
September 2025
Department of Animal Science, South Dakota State University, Brookings, SD 57007, USA.
Flaxseed oil contains elevated levels of omega-3 fatty acids (n-3 FA), which have been shown to impact reproductive performance. This study aimed to determine the effects of a flaxseed oil-based supplement on reproductive parameters, feeding behavior, and lipid profile in beef heifers. Sixty Angus and Simmental × Angus heifers (14 months old ± 2 months), blocked by full body weight (BW; 396.
View Article and Find Full Text PDFInflammopharmacology
September 2025
Department of Surgery, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Objective: This study evaluated the effects and mechanisms of antioxidant and anti-inflammatory oils with a high omega-9:omega-6 ratio and a low omega-6:omega-3 ratio on post-extraction healing in rats.
Materials And Methods: A total of 128 Wistar rats were divided into four groups: Sham, Saline, Isolipidic, and Anti-inflammatory/Antioxidant. The animals received one of the following treatments: (1) 0.
Clin Transl Allergy
September 2025
Department of Woman, Child and of General and Specialized Surgery, AOU University of Campania "Luigi Vanvitelli", Naples, Italy.
Background: Fel d 1, the primary allergen produced by cats, is a glycoprotein found mainly in their salivary and sebaceous glands. Due to its small size and stability, it easily becomes airborne and adheres to surfaces, posing a persistent problem for allergic individuals.
Methods: This article reviews innovative strategies aimed at reducing Fel d 1 expression and exposure and mitigating its allergic effects on humans.