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Background: Intrasaccular flow disruption with WEB is a safe and efficacious technique that has significantly changed endovascular management of wide-neck bifurcation aneurysms (WNBAs). Use of stent in combination with WEB is occasionally required. We analyzed the frequency of use, indications, safety, and efficacy of the WEB-stent combination.
Methods: All aneurysms treated with WEB and stent were extracted from a prospectively maintained database. Patient and aneurysm characteristics, complications, and anatomical results were independently analyzed by a physician independent of the procedures.
Results: From June 2011 to January 2020, 152 patients with 157 aneurysms were treated with WEB. Of these, 17/152 patients (11.2%) with 19/157 aneurysms (12.1%) were treated with WEB device and stent. Indications were very wide neck with a branch emerging from the neck in 1/19 (5.2%) aneurysms and WEB protrusion in 18/19 (94.7%). At 1 month, no morbimortality was reported. At 6 months, anatomical results were complete aneurysm occlusion in 15/17 aneurysms (88.2%), neck remnant in 1/17 (5.9%), and aneurysm remnant in 1/17 (5.9%). At 12 months, there was complete aneurysm occlusion in 13/14 aneurysms (92.9%) and neck remnant in 1/14 (7.1%).
Conclusions: Combining WEB and stent is a therapeutic strategy to manage WNBA. In our series, this combination was used in 11.2% of patients treated with WEB, resulting in no morbidity or mortality with a high efficacy at 6 and 12 months (complete aneurysm occlusion in 88.2% and 92.9%, respectively).
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http://dx.doi.org/10.1136/neurintsurg-2021-017379 | DOI Listing |
J Robot Surg
September 2025
Department of Pediatric Surgery, Affiliated Hospital of North Sichuan Medical College (Wenhua Road Campus), No. 57, Section 2 of Wenhua Road, Shunqing District, Nanchong City, 637000, Sichuan Province, People's Republic of China.
This study aims to systematically assess the therapeutic effectiveness of TiRobot-assisted percutaneous kyphoplasty or vertebroplasty in managing osteoporotic thoracolumbar compression fractures. Previous studies have suggested that TiRobot-assisted techniques outperform conventional manual procedures in treating this condition, but relevant conclusions remain controversial. A thorough literature retrieval was carried out across 4 major databases: PubMed, Embase, the Cochrane Library, and Web of Science.
View Article and Find Full Text PDFBr J Sports Med
September 2025
Oslo Sports Trauma Research Center, Norwegian School of Sports Sciences, Oslo, Norway.
Objective: To describe the proposed biomedical effect mechanisms in research on exercise-based injury prevention programmes in football (soccer) and handball.
Design: Scoping review of randomised controlled trials (RCT), cohort studies and case studies.
Data Sources: MEDLINE via PubMed, SPORTDiscus and Web of Science databases were searched from 2000 to 2024.
BMJ Open
September 2025
School of Exercise and Health, Shanghai University of Sport, Shanghai, China
Introduction: Although emerging evidence supports the short-term efficacy of transcranial magnetic stimulation (TMS), including repetitive TMS (rTMS) and theta-burst transcranial magnetic stimulation (TBS-TMS), and transcranial direct current stimulation (tDCS) for managing patients with chronic musculoskeletal pain (CMP), their clinical utility in managing CMP remains inconclusive. This uncertainty may arise from methodological limitations, including heterogeneity in treatment parameters such as stimulation targets and dosages. Additionally, safety profiles for these non-invasive brain stimulation interventions in patients with CMP remain insufficiently reported, with limited data on adverse events, cumulative risks and long-term safety outcomes.
View Article and Find Full Text PDFBMJ Open
September 2025
Nursing School, Ningxia Medical University, Yinchuan, Ningxia, China.
Background: Nasopharyngeal carcinoma (NPC) presents significant nutritional challenges during concurrent chemoradiotherapy, adversely affecting treatment outcomes and quality of life. Non-pharmacological interventions may help improve nutritional and immune status, reduce complications and enhance overall well-being. However, evidence of their effectiveness is scattered and inconsistent, and no systematic review has yet synthesised the evidence on their effectiveness.
View Article and Find Full Text PDFBMJ Open
September 2025
Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang, Liaoning, Chinax
Objectives: This study evaluated the effects of proximal core training on biomechanical risk factors and strength parameters in individuals at high risk of anterior cruciate ligament (ACL) injury (specifically: those exhibiting pathological movement patterns, neuromuscular deficits or biomechanical risk factors) and compared direct versus indirect interventions. We hypothesised that targeted training enhances dynamic knee stabilisation and hip control during high-risk manoeuvres, with direct approaches providing superior biomechanical benefits through neuromuscular control optimisation.
Design: Systematic review and meta-analysis using the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) approach.