Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: In March 2020, the World Health Organization (WHO) declared COVID-19 a public health emergency of international concern. A small proportion of patients infected with COVID-19 go on to develop pneumonia. We speculated that COVID-19 may be likely to result in psychological disorders such as anxiety and depression. In this study, we conducted an investigation of anxiety and depression in patients with COVID-19.
Methods: Sixty-five COVID-19 patients were randomly enrolled into this study. Anxiety and depression among participants were measured through the completion of anonymous Chinese-language Zung self-rating anxiety scale and self-rating depression scale questionnaires. Data were analyzed using independent samples t-tests, Mann-Whitney U-tests, and χ2 tests.
Results: The questionnaire results showed that 26.15% and 41.54% of participants suffered from anxiety and depression, respectively, although there was no significantly statistical difference between the proportions of COVID-19 patients with anxiety and depression. Statistically significant differences in employment status, partial pressure of oxygen, and corticosteroid application existed between moderate- and severe COVID-19 patients (P<0.05). In particular, the partial pressure of oxygen was significantly lower in severe COVID-19 patients than in their moderate counter parts (71.31±23.54 vs. 101.06±34.43, U=156, P=0.006). Total lymphocytes was lower in severe group than in moderate group [1.659±0.643 vs. 0.745 (0.645, 0.928), U=109, P=0.000]. Also, a higher proportion of female than male patients had anxiety (χ2=5.388, P=0.02). COVID-19 patients who received antiviral medications also displayed a higher rate of anxiety (χ2=4.481, P=0.034). Total lymphocytes between the non-anxiety and anxiety had statistical difference (U=321, P=0.019). Meanwhile, total lymphocytes between the non-depression and depression also had statistical difference (U=389.5, P=0.01).
Conclusions: Among patients with COVID-19, females and those treated with antiviral medications were more likely to experience anxiety. In addition, our findings reflected the effect of anxiety and depression on immune system.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.21037/apm-21-212 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Safety Threats of Seasonal and Non-Seasonal Natural Disasters Increase Disaster Anxiety and Disaster Risk Perception.
Scand J Psychol
September 2025
Faculty of Psychology, University of Akureyri, Akureyri, Iceland.
Living under the threat of natural disasters affects mental health. Natural disasters that are more likely to occur in a specific season represent a special case that is becoming more frequent with the consequences of climate change. Therefore, they deserve special attention regarding their potentially seasonal mental health implications.
View Article and Find Full Text PDFArt therapy with children and adolescents experiencing acute or severe mental health conditions: A systematic review.
Aust N Z J Psychiatry
September 2025
Department of Psychological Medicine, Sydney Children's Hospitals Network, Sydney, NSW, Australia.
Objective: Art therapy offers a predominantly non-verbal form of creative self-expression for people experiencing mental health issues. This systematic review aims to investigate the effectiveness and acceptability of art therapy for children and adolescents experiencing acute or severe mental health conditions.
Methods: Following PRISMA guidelines, five electronic databases were searched (Embase, MEDLINE, Web of Science Core Collection, PsychINFO, CINAHL) using the search terms ('art therap*' OR 'art psychotherap*') AND ('child*' OR 'adolescen*' OR 'youth' OR 'young' OR 'teen*').
Network Analysis of Problematic Internet Use and Adolescent Psychological Issues: The Role of Socioeconomic Status.
Cyberpsychol Behav Soc Netw
September 2025
School of Nursing and Rehabilitation, Shandong University, Jinan, China.
This study examined the interplay between anxiety, depression, rumination, and problematic internet use (PIU) among 24,470 Chinese adolescents (mean age = 14.37 years; 51.60 percent male), with particular attention to socioeconomic status (SES) variations.
View Article and Find Full Text PDFSleep Quality in Chronic Pain Patients With and Without Strong Opioid Use: An Observational Study Using a Wearable Device.
Neuropsychopharmacol Rep
September 2025
Department of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan.
Background: Although opioid analgesics may influence sleep in patients with chronic pain, the association between strong opioid use and sleep characteristics remains unclear. This study aimed to explore differences in sleep status among chronic pain patients with varying levels of opioid use.
Methods: A total of 29 patients with chronic non-cancer pain who had been under treatment for more than 6 months were included.
Associations between psychotic experience dimensions and polygenic liability to schizophrenia in a longitudinal birth cohort.
BJPsych Open
September 2025
Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Population Health Sciences, Bristol Medical School, Bristol, UK.
Background: Some psychotic experiences in the general population show associations with higher schizophrenia and other mental health-related polygenic risk scores (PRSs), but studies have not usually included interviewer-rated positive, negative and disorganised dimensions, which show distinct associations in clinical samples.
Aims: To investigate associations of these psychotic experience dimensions primarily with schizophrenia PRS and, secondarily, with other relevant PRSs.
Method: Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort participants were assessed for positive, negative and disorganised psychotic experience dimensions from interviews, and for self-rated negative symptoms, at 24 years of age.