Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

The magnetically suspended control and sense gyroscope (MSCSG) integrates spacecraft attitude measurement and control function; this paper proposes a double spherical rotor (DSR) for MSCSG. The DSR realizes the five degrees of freedom (DOFs) full active control and full channel magnetic path decoupling by the following design: the spherical axial/radial reluctance magnetic bearings are adopted to control the 3DOFs translation of rotor in the range of double spherical envelope, Lorentz force magnetic bearing (LFMB) is used to precisely drive the 2DOFs universal deflection of rotor. The optimization model is established based on the structural mechanical analysis, taking the deviation between rotor centroid and shape center as the optimization objective, choosing the first order resonance frequency, maximum equivalent stress, rigid body displacement, polar moment of inertia and inertia ratio as constraints. Then the DSR is optimized and simulated by the finite element, the MSCSG principle prototype based on DSR is successfully developed, the online dynamic balance experiment and modal test of the DSR are conducted, where the vibration amount of the DSR decreases from 20 μm before the experiment to 0.14 μm after the experiment, which decreases by 99.3%, the first test modal is 2881 Hz which is 5% different from the finite element simulation value of 3034 Hz. The results show that the DSR has the good mechanical properties and magnetic circuit decoupling characteristics.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358513PMC
http://dx.doi.org/10.1177/0036850421998488DOI Listing

Publication Analysis

Top Keywords

double spherical
12
spherical rotor
8
finite element
8
dsr
7
rotor
5
optimal design
4
experiment
4
design experiment
4
experiment study
4
study double
4

Similar Publications

Purpose: To report clinical outcomes in patients implanted with an isofocal optic-design intraocular lens (IOL) with double C-loop haptics following cataract surgery.

Methods: This was a multicentre-prospective-study involving 108 eyes (54 subjects) implanted with the Isopure Serenity (BVI, Inc). IOL.

View Article and Find Full Text PDF

An ultrasensitive biosensor for H1N1 virus coupled with 3D spherical DNA nanostructure and CRISPR-Cas12a.

Spectrochim Acta A Mol Biomol Spectrosc

September 2025

Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, China. Electronic address:

To achieve ultrasensitive and real-time detection of the H1N1 influenza virus, this study designed a nucleic acid-free fluorescent biosensor based on 3D spherical DNA nanostructure and CRISPR/Cas12a (3D-SDNC). The biosensor constructs a rigid 3D nano-framework via self-assembly of six oligonucleotide chains, with H1N1-specific nucleic acid aptamers and Cas12a activator strands strategically positioned at multi-spined vertices for precise spatial coupling between viral recognition and signal transduction. Upon aptamer-virus binding, the induced conformational change liberates the activator strand, thereby activating the trans-cleavage activity of the Cas12a/crRNA complex to efficiently cleave the HEX/BHQ1 double-labeled fluorescent probe and initiate cascade signal amplification.

View Article and Find Full Text PDF

Large bone defects present significant clinical challenges, with distraction osteogenesis (DO) requiring prolonged treatment periods and yielding suboptimal outcomes. Calcitonin gene-related peptide (CGRP) demonstrates potent bone-forming activity but suffers from rapid degradation and a short half-life, limiting its therapeutic applications. This study engineered sustained-release CGRP microspheres using poly(D,L-lactide-co-glycolide)/nano-hydroxyapatite/graphene oxide (PLGA/nHA/GO) composite matrices via W/O/W double emulsion-solvent evaporation method to address these limitations.

View Article and Find Full Text PDF

Chaga mushroom (Inonotus obliquus) exhibits cytotoxic effects against breast cancer cells. Mycosynthesized nanoparticles, owing to their biodegradability, biocompatibility, and low toxicity, present a promising therapeutic approach. This study explored the cytotoxic potential of gold nanoparticles synthesized using Chaga mushroom extract (AuCh-NPs) combined with Light Emitting Diode (LED) irradiation (530 nm) on human breast cancer (MCF-7) cells, aiming to develop a safe and effective sensitizer for photothermal therapy.

View Article and Find Full Text PDF

Postoperative ocular inflammation is a frequent complication of eye surgeries commonly managed using corticosteroids or nonsteroidal anti-inflammatory drug (NSAIDs) eye drops. However, poor ocular bioavailability and patient non-adherence due to frequent dosing limit the therapeutic efficacy of conventional eye drops. This study aimed to develop a sustained-release ocular insert containing bromfenac sodium (BS)-loaded poly(lactic-co-glycolic acid) (PLGA) microparticles (MPs) with an initial 3% (/) free BS fraction incorporated into a poly(vinyl alcohol) (PVA) matrix designed to achieve a dual-phase release profile for improved postoperative therapy.

View Article and Find Full Text PDF