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The recent publication of the revised Consensus on definition and diagnosis of sarcopenia (EWGSOP2) and the Global Leadership Initiative on Malnutrition (GLIM) criteria changed the approach to research on sarcopenia and malnutrition. Whilst sarcopenia is a nutrition-related disease, malnutrition and cachexia are nutritional disorders sharing the common feature of low fat-free mass. However, they have differential characteristics and etiologies, as well as specific therapeutic approaches. Applying the current definitions in clinical practice is still a challenge for health professionals and the potential for misdiagnosis is high. This is of special concern in the subgroup of older people with cancer, in which sarcopenia, malnutrition, and cancer cachexia are highly prevalent and can overlap or occur separately. The purpose of this review is to provide an updated overview of the latest research and consensus definitions of sarcopenia, malnutrition, and cachexia and to discuss their implications for clinical practice in older patients with cancer. The overall aim is to improve the quality of nutritional care in light of the latest findings.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996854 | PMC |
http://dx.doi.org/10.3390/nu13030761 | DOI Listing |
Clin Nutr
August 2025
Critical Care Medicine, Yokohama City University Hospital, Kanagawa, Japan.
Background: The Global Leadership Initiative on Malnutrition (GLIM) lacks endorsed criteria for a muscle mass assessment. Since a muscle mass assessment using trunk computed tomography (CT) cannot be performed on all patients, a temporal muscle evaluation may serve as an useful alternative. In the present study, we hypothesized that complementing a total skeletal muscle mass assessment with a temporal muscle evaluation may provide a viable strategy for the GLIM assessment in the intensive care unit (ICU).
View Article and Find Full Text PDFJ Frailty Aging
September 2025
Division of Human Nutrition and Health, Wageningen University, P.O. Box 17, 6700, AA, Wageningen, Netherlands.
Introduction: Sarcopenia, a progressive age-related loss of skeletal muscle mass and function, poses significant health risks in older adults. Phase angle (PhA), derived from bioimpedance analysis, has been proposed as an indicator of muscle quality and physical functioning. This study investigates the association between PhA and physical function, and its potential utility in case-finding phase of sarcopenia assessment based on EWGSOP2 functional cut-offs.
View Article and Find Full Text PDFFront Public Health
September 2025
Department of Geriatrics, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Background: Malnutrition is a prevalent but underrecognized health issue among older adults in China. Inadequate awareness may delay detection and intervention, especially in cognitively vulnerable populations. To assess the level of malnutrition awareness and its association with sociodemographic, cognitive, and nutritional factors in a representative sample of older Chinese adults.
View Article and Find Full Text PDFRadiologie (Heidelb)
September 2025
Department of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Adnan Menderes Bulvarı (Vatan Street), 34093, Fatih, Istanbul, Turkey.
Purpose: The aim of this study was to investigate the relationship between temporal muscle thickness (TMT) as well as temporal (TMA) and masseter muscle (MMA) area with nutritional status and sarcopenia in older individuals.
Methods: This was a retrospective cross-sectional study. A total of 275 participants were evaluated to establish comprehensive geriatric assessment guidelines.
Inn Med (Heidelb)
September 2025
Institut für Biomedizin des Alterns, Friedrich-Alexander-Universität Erlangen-Nürnberg, Kobergerstraße 60, 90408, Nürnberg, Deutschland.
Nutrition is considered to play a key role in the multifactorial development of frailty. Conversely, frailty also affects nutrition. The aim of this article is to describe the interactions between these two entities in detail and to derive nutritional recommendations.
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