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Purpose: The COVID-19 pandemic has affected healthcare systems globally, leading to reorganization of medical activities. We performed an international survey aimed to investigate the medium- and long-term impact on oncology units.
Materials And Methods: An 82-item survey was distributed from June 17 to July 14, 2020 among medical oncologists worldwide.
Results: One hundred nine medical oncologists from 18 countries in Europe (n = 93), United States (n = 5), and Latin America (n = 11) answered the survey. A systematic tracing of COVID-19-positive patients was continued in the postacute phase by 77.1% of the centers; 64.2% of the respondents participated in a local registry and 56% in international or national registries of infected patients. Treatment adaptations were introduced, and surgery was the most affected modality being delayed or canceled in more than 10% of patients in 34% of the centers, whereas early cessation of palliative treatment was reported in 32.1% of the centers; 64.2% of respondents reported paying attention to avoid undertreatments. The use of telemedicine has been largely increased. Similarly, virtual tools are increasingly used particularly for medical education and international or national or multidisciplinary meetings. 60.6% of the participants reduced clinical activity, and 28.4% compensated by increasing their research activity. Significant reduction of clinical trial activities is expected in 37% of centers this year. The well-being of healthcare staff would not recover by the end of the year according to 18% of the participants.
Conclusion: The COVID-19 outbreak has had a major impact on oncologic activity, which will persist in the future, irrespective of geographical areas.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081548 | PMC |
http://dx.doi.org/10.1200/GO.20.00589 | DOI Listing |
BioDrugs
September 2025
Department of Nephrology, Instituto de Investigación Hospital "12 de Octubre" (imas12), Avda. De Córdoba s/n, 28041, Madrid, Spain.
Anti-CD20 monoclonal antibodies are gaining clinical relevance in the nephrology community due to their demonstrated efficacy and favorable safety profiles across short-, medium-, and long-term use. Initially developed for hematologic malignancies and multiple sclerosis, B-cell depletion therapies are now being investigated across a broader spectrum of autoimmune diseases, including glomerulopathies, both with and without associated podocytopathy. Recent advances have led to the development of novel anti-CD20 agents that are being used not only as potential alternatives to corticosteroids but also as adjunctive therapies in complex clinical settings.
View Article and Find Full Text PDFFront Microbiol
August 2025
State Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Introduction: Manganese-oxidizing bacteria (MOB) play a critical role in converting soluble Mn(II) to insoluble Mn(III/IV) oxides, which have been widely applied for environmental remediation, particularly in heavy metal pollution control. Therefore, the discovery of novel MOB strains is of great significance for advancing pollution mitigation and ecosystem restoration.
Methods: In this study, a manganese-oxidizing bacterial strain was isolated from Mn-contaminated soil near an electroplating factory using selective LB medium supplemented with 10 mmol/L manganese chloride (MnCl), and the Leucoberbelin Blue (LBB) assay was employed to screen and identify strains with strong Mn(II)-oxidation ability.
J Nurs Manag
September 2025
Division of Health Science, Graduate School of Medicine, The University of Osaka, 1-7 Yamadaoka, Suita, Osaka 565-0871, Japan.
In many developed countries, a rapidly aging population has increased healthcare demands and the proportion of older nurses in the workforce. This demographic shift requires nursing managers to have a deeper understanding of the physical demands on staff nurses, particularly older ones. In this paper, we aim to provide valuable insights for developing evidence-based strategies to improve work environments in hospital wards.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
Institute of Plant Protection, Jilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Gongzhuling 136100, China. Electronic address:
Long-term large-scale application of acetochlor has led to its accumulation in soil, causing serious environmental pollution. In this study, Klebsiella michiganensis ES15 was isolated from the contaminated reactive sludge of an acetochlor pesticide plant and achieved 79.23 % degradation of acetochlor within 4 d after medium optimization using response surface methodology.
View Article and Find Full Text PDFUrol J
September 2025
Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Purpose: Men with lower urinary tract symptoms (LUTS) from benign prostatic hyperplasia (BPH) often experience erectile dysfunction (ED). While transurethral resection of the prostate (TURP) can improve ED, new-onset ED remains a concern. This study compares monopolar (M-TURP) and bipolar (B-TURP) techniques, with a subgroup analysis based on phosphodiesterase-5 inhibitor (PDE5i) use.
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