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This study investigated the impact of feeding pelleted diets containing camelina ( L. Crantz) hay (CAHP) or camelina meal (CAMP) as a supplement compared with a control pellet (CONP) diet, without vitamin E fortification. The fatty acid profile, retail colour, and lipid oxidative stability of lamb and yearling meat () stored for short-, medium-, or long-periods (2 days (fresh), 45 days and 90 days) under chilled to semi-frozen conditions were determined. The CAMP diet altered key fatty acids ( < 0.05) in a nutritionally beneficial manner for human health compared to the other diets, with increased total omega-3, decreased omega-6 fatty acids and decreased omega-6/omega-3 ratio of muscle. Muscle vitamin E concentration was lower ( < 0.05) for both camelina diets (CAMP and CAHP) when compared with the CONP diet, with the average concentrations less than 1 mg/kg muscle for all three treatments. Animal type and storage length were factors that all affected ( < 0.05) colour and lipid oxidative stability of meat. These results emphasise the importance of vitamin E concentration in meat stored for extended periods under semi-frozen conditions to maintain desirable meat colour during retail display, and to avoid off-flavour development of the cooked meat.
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http://dx.doi.org/10.3390/antiox10020166 | DOI Listing |
Reprod Domest Anim
September 2025
Department of Animal Reproduction and Artificial Insemination, University of Ondokuz Mayis, Samsun, Turkey.
Cryopreservation of ram sperm is a cornerstone in reproductive biotechnology but is often accompanied by oxidative damage that compromises post-thaw sperm quality. Curcumin, a natural polyphenol with potent antioxidant properties, may offer protection against cryo-induced injuries. This study evaluated the effects of curcumin supplementation at two concentrations (10% and 20%) in semen extenders on the functional and molecular characteristics of ram spermatozoa.
View Article and Find Full Text PDFJ Med Chem
September 2025
Chemistry, Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States.
Targeting CDK2 with first generation CDK2 inhibitors suffered from a reduced therapeutic index likely due to toxicity stemming from lack of selectivity against the CDK family and other kinases. Recently, CDK2 has been identified as a mediator of resistance to CDK4/6 inhibitors in the context of high levels of cyclin E expression. Discovery of highly selective CDK2 inhibitors may minimize off-target effects, reduce toxicity observed with first generation CDK2 inhibitors, and allow precise targeting of aberrant cell cycle progression and resistance mechanisms mediated by high cyclin E/CDK2 activity.
View Article and Find Full Text PDFBMC Plant Biol
September 2025
Key Laboratory of Grassland Resources of the Ministry of Education, College of Grassland Science, Inner Mongolia Agricultural University, Hohhot, 010011, China.
Background: Grazing, as one of the most important methods of utilizing natural grasslands, can significantly impact the accumulation and stabilization of soil organic carbon within grassland ecosystems. Soil microbial necromass carbon (MNC), including fungal necromass carbon (FNC) and bacterial necromass carbon (BNC), is an important source of soil organic carbon (SOC) and plays a critical role in the formation and stabilization of SOC. However, the effects of grazing intensity on soil MNC and its underlying drivers remain unclear.
View Article and Find Full Text PDFMicroorganisms
July 2025
Provincial Key Laboratory of Conservation Biology, School of Forestry, Jiangxi Agricultural University, Nanchang 330045, China.
Deadwood is essential for the forest ecosystem productivity and stability. A growing body of evidence indicates that deadwood-inhabiting microbes are effective decomposition agents, yet little is known about how changes in microbial communities during the initial deadwood decay. In a small forest area, we performed dense sampling from the top, middle, and bottom portions of two representative cultivars logs to track deadwood xylem microbiota shift during the initial deadwood decay.
View Article and Find Full Text PDFACS Biomater Sci Eng
August 2025
Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, Florida 33136, United States.
Improvements in osseointegration and bone healing as a result of surface modifications indicate that the time frame following implantation necessary to achieve biomechanical capacity for functional load-bearing may be reduced. In this context, a potassium peroxymonosulfate-based modified triple salt monolayer could potentially serve as a viable surface coating to further augment bone regenerative capabilities of endosteal implants. Implants with resorbable blast media textured surface [Tapered Pro 3DS RBT (Laser-Lok), BioHorizons] (CTRL) were treated with a potassium peroxymonosulfate-based modified triple salt coating process to generate a stabilized monolayer (Oxion).
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