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Background: The accuracy of the National Task Group-Early Detection Screen for Dementia (NTG-EDSD) was evaluated in a sample of 185 adults with Down syndrome (DS), emphasizing 'mild cognitive impairment (MCI-DS)'.
Method: Knowledgeable informants were interviewed with the NTG-EDSD, and findings were compared to an independent dementia status rating based on consensus review of detailed assessments of cognition, functional abilities and health status (including physician examination).
Results: Results indicated that sections of the NTG-EDSD were sensitive to MCI-DS, with one or more concerns within the 'Memory' or 'Language and Communication' domains being most informative.
Conclusions: The NTG-EDSD is a useful tool for evaluating dementia status, including MCI-DS. However, estimates of sensitivity and specificity, even for detecting frank dementia, indicated that NTG-EDSD findings need to be supplemented by additional sources of relevant information to achieve an acceptable level of diagnostic/screening accuracy.
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http://dx.doi.org/10.1111/jar.12849 | DOI Listing |
Sci Bull (Beijing)
August 2025
Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:
Reciprocity is considered one of the vital mechanisms that sustain the evolution of cooperative behavior. However, free-riding, where assistance is received but not reciprocated, poses a serious threat to reciprocity behavior, which relies on future payback. Previous theories proposed that third-party punishment plays a vital role in preventing free-riding behavior.
View Article and Find Full Text PDFInt J Psychophysiol
September 2025
National Research Institute of Police Science, 6-3-1 Kashiwanoha, Kashiwa, Chiba, 277-0882, Japan. Electronic address:
The autonomic-based Concealed Information Test (CIT) focuses on differential responses to a crime-relevant item that is significant only for knowledgeable persons. This study examined whether pre-test instructions on question themes defining knowledgeable and unknowledgeable contexts modulate the magnitude of differential responses to the relevant item. The participants (36 men 46 women) were instructed to steal one item from one of two possible locations in a mock theft task.
View Article and Find Full Text PDFAnn N Y Acad Sci
September 2025
Clinical Medicine and Advanced Applied Research Department, Point Robotics Medtech Incorporation, Taipei, Taiwan.
People with psychotic experiences (PE) have movement abnormalities, including slow movements and uncontrolled movements, which are indicative of transition to psychotic disorders. Rhythmic auditory cueing (RAC) has been indicated to be a promising therapeutic technique for movement abnormalities in people in the psychosis continuum; however, small sample size limited the strength of that conclusion. The aims of our study were to increase the sample size, adopt a repeated measures design, and examine if faster RAC induced faster movements and less uncontrolled movements in both hands in people with PE.
View Article and Find Full Text PDFSurgery
September 2025
Department of Surgery, University of Chicago, Chicago, IL. Electronic address: https://twitter.com/selwyn_rogers.
Public policy and health care are demonstrably interconnected. Medical and surgical outcomes are inseparableable from the political processes and laws that govern our nation. Health care delivery and public health are shaped by public discourse in city councils, county commissions, and state/national legislatures and agencies.
View Article and Find Full Text PDFJMIR Hum Factors
September 2025
Villa Beretta Rehabilitation Center, Costa Masnaga, Italy.
Background: Telerehabilitation is a promising solution to provide continuity of care. Most existing telerehabilitation platforms focus on rehabilitating upper limbs, balance, and cognitive training, but exercises improving cardiovascular fitness are often neglected.
Objective: The objective of this study is to evaluate the acceptability and feasibility of a telerehabilitation intervention combining cognitive and aerobic exercises.