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Objectives: To examine if exposure to maternal smoking during pregnancy is associated with emergency department (ED) presentation and admission through the ED in children up to 5 years after birth.
Methods: Antenatal records of all children up to 5 years of age who were born in Tasmania, Australia, between July 2008 and June 2014 were linked to health service use (ED presentations and hospital admissions). Negative binomial regression was used to estimate the incidence rate ratio (IRR) and 95% confidence intervals (CIs) at ≤1 year and ≤5 years for ED presentations and admissions to the hospital through the ED for any reason and by 9 major disease categories for children exposed versus children not exposed to maternal smoking during pregnancy. Models were adjusted for sex, socioeconomic position, maternal age at birth, and region of residence. Presentations and admissions for poisoning and injuries were used as a negative control.
Results: Among 36 630 infants, 21% were exposed to maternal smoking during pregnancy. Exposed children had a 26% higher rate of presentation to the ED (IRR 1.26; 95% CI 1.23-1.29) and a 45% higher rate of admission (IRR 1.45; 95% CI 1.39-1.51) at up to 5 years of age. Compared with the negative control, higher presentation and admission rates were evident in respiratory; eyes, ears, nose, and throat; psychosocial; and infectious disease categories.
Conclusions: Higher health care service use was observed in children exposed to maternal smoking during pregnancy for a range of conditions associated with exposure to smoking. The findings reinforce the need to reduce smoking among people in their childbearing years.
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http://dx.doi.org/10.1542/hpeds.2020-0150 | DOI Listing |
Ann Intern Med
September 2025
Department of Medicine, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada (J.G.R.).
Background: Animal studies show ovarian follicle damage and mutagenesis after ionizing radiation exposure. Computed tomography (CT) imaging is commonly done outside pregnancy, but risks to future pregnancy are unknown.
Objective: To evaluate the risk for spontaneous pregnancy loss and congenital anomalies in offspring of women exposed to CT ionizing radiation before conception.
BJOG
September 2025
Department of Obstetrics and Gynaecology, Melbourne Medical School, The University of Melbourne, Melbourne, Victoria, Australia.
Objectives: To examine the combined influence of food environment, built environment, socio-economic status and individual factors (maternal age, parity, smoking status and need for an interpreter) on maternal overweight, gestational diabetes mellitus (GDM) and large-for-gestational age (LGA) births in Australia.
Design: Retrospective cohort study.
Setting: Melbourne, Australia.
Health Promot J Austr
October 2025
School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.
Issue Addressed: Smoking during pregnancy poses serious health risks for mother and baby. Addressing smoking among pregnant Aboriginal and Torres Strait Islander women is an Australian national priority. This study aimed to understand the geographical variation in rates of not smoking during pregnancy among Aboriginal and Torres Strait Islander women.
View Article and Find Full Text PDFSleep Med
August 2025
Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Zuid-Holland, the Netherlands; Trimbos Institute - Netherlands Institute for Mental Health and Addiction, Utrecht, the Netherlands. Electronic address:
Objectives: Sleep is known to change around pregnancy. Yet current studies often do not take into account the multidimensionality of sleep and its changes from preconception to postpartum. Therefore, this study aims to explore maternal multivariate sleep trajectory from preconception to 6 months postpartum and related determinants.
View Article and Find Full Text PDFInt J Gynecol Cancer
August 2025
Northwell Health, Zucker School of Medicine at Hofstra/Northwell, Long Island Jewish Medical Center, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, New Hyde Park, NY, USA; Northwell Health, Feinstein Institutes for Medical Research, Institute of Molecular Medicine, Manhas
Objective: The purpose of this study was to evaluate whether the combination of cefazolin or a second-generation cephalosporin plus metronidazole is associated with a reduced risk of surgical site infection in women undergoing hysterectomy for gynecologic cancer compared to using cefazolin or a second-generation cephalosporin alone.
Methods: This was a retrospective cohort study of patients who underwent hysterectomy at a single institution between January 2020 and June 2022. The primary outcome was surgical site infection.