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http://dx.doi.org/10.3389/fmicb.2020.538209 | DOI Listing |
Cardiovasc Res
September 2025
Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford.
Neurol Genet
April 2025
Department of Human Genetics, University of Utah, Salt Lake City; and.
Int J Mol Sci
August 2025
Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, 30-239 Krakow, Poland.
Cytochrome P450 (CYP450) enzymes play an essential role in the metabolism of drugs, particularly in phase I metabolic reactions. In this article, we present a comprehensive review of fifteen selected enzymes belonging to the CYP450 family. The enzymes included in this analysis are CYP7A1, CYP3A4, CYP3A5, CYP2D6, CYP2E1, CYP2C8, CYP2C18, CYP2C9, CYP2C19, CYP2B6, CYP2A6, CYP2A13, CYP1B1, CYP1A1, and CYP1A2.
View Article and Find Full Text PDFScience
August 2025
Department of Biology, University of Copenhagen, Copenhagen, Denmark.
To get more out of genome sequences, the effects of variants need to be quantified.
View Article and Find Full Text PDFCardiovasc Res
August 2025
Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.