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Background And Aim: Infertility affects ~20% of the couples in the world. Assisted reproductive technologies (ARTs) are currently the most common treatment option for infertility. Nevertheless, ARTs may be associated with complications for mothers and/or offspring. Natural procreative technology (NaProTechnology) is a natural treatment which minimizes these risks by seeking to identify the causes of infertility to enable better treatments. This narrative review summarizes the complications related to ARTs and clarifies how the NaProTechnology approach can help ARTs to achieve better results or be used in alternative to ARTs.
Methods: Data in the literature indicate that NaProTechnology is a natural approach for treating infertility.
Results: The percentage of live births obtained by NaProTechnology is similar to that of ARTs.
Conclusions: An extensive search for the genetic defects causing infertility or subfertility through genetic testing can help both ARTs and NaProTechnology to achieve successful pregnancies. By discovering the underlying causes of infertility, genetic tests enable better family counseling, like the implications of transmitting risk- and disease-alleles to future generations.
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http://dx.doi.org/10.23750/abm.v91i13-S.10525 | DOI Listing |
Int J Neonatal Screen
August 2025
CEINGE Advanced Biotechnologies Franco Salvatore, s.c.a r.l., 80145 Naples, Italy.
Three targeted therapies are currently available for spinal muscular atrophy (SMA), which have dramatically changed the natural history of this severe and potentially fatal disease. More than 95% of SMA cases have a homozygous deletion of exon 7 of the gene. Disease expression mainly depends on the copy number of , a hypomorphic copy of .
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March 2025
Clinical Pharmacy and Pharmacy Management, University of Nigeria Faculty of Pharmaceutical Sciences, Nsukka, Enugu, Nigeria.
Objective: The study assessed the knowledge, awareness and perception of NaProTechnology as well as the effect of an educational video intervention among pharmacy undergraduate students.
Design: The study design was a pre-post educational video intervention using a cross-sectional questionnaire-based survey.
Participants And Setting: The study was done among undergraduate students of a school of pharmacy in South-eastern Nigeria.
Monash Bioeth Rev
June 2025
Swinburne University of Technology, John St, Hawthorn, VIC, 3122, Australia.
Hum Reprod Open
August 2022
Novant Health Triad Obstetrics & Gynecology, Winston-Salem, NC, USA.
Study Question: What is the feasibility of a prospective protocol to follow subfertile couples being treated with natural procreative technology for up to 3 years at multiple clinical sites?
Summary Answer: Overall, clinical sites had missing data for about one-third of participants, the proportion of participants responding to follow-up questionnaires during time periods when participant compensation was available (about two-thirds) was double that of time periods when participant compensation was not available (about one-third) and follow-up information was most complete for pregnancies and births (obtained from both clinics and participants).
What Is Known Already: Several retrospective single-clinic studies from Canada, Ireland and the USA, with subfertile couples receiving restorative reproductive medicine, mostly natural procreative technology, have reported adjusted cumulative live birth rates ranging from 29% to 66%, for treatment for up to 2 years, with a mean women's age of about 35 years.
Study Design Size Duration: The international Natural Procreative Technology Evaluation and Surveillance of Treatment for Subfertility (iNEST) was designed as a multicenter, prospective cohort study, to enroll subfertile couples seeking treatment for live birth, assess baseline characteristics and follow them up for up to 3 years to report diagnoses, treatments and outcomes of pregnancy and live birth.
Evol Psychol
October 2021
Evolutionary Psychology: Human History as Natural History.
At the beginning of our era, after a battle on the Ionian Sea, Antony and Cleopatra took their own lives in Egypt, and Augustus was made an by his senators Roman emperors had sexual access to those senators' daughters and wives, and to thousands of slaves. But they ran governments with help from their castrated civil servants. And they enforced an Imperial Cult: subjects made sacrifices to the emperor's or procreative spirit; or they got disemboweled by wild animals, or decapitated.
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