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An interrupted aortic arch (IAA) is a rare type of congenital heart disease, and few patients survived into the adulthood. Surgical reconstruction is still the recommended approach, despite its complexity and considerable complication. In addition, patients with IAA usually suffer from several other important congenital heart anomalies, which increase the complexity of surgical management of IAA. Although endovascular therapy has replaced surgery in the treatment of the majority of non-IAA, its applicability in IAA is still matter of debate. In the present review, we have discussed about various therapeutic solutions of IAA, and present a stepwise approach for its endovascular management.
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http://dx.doi.org/10.1016/j.cpcardiol.2020.100717 | DOI Listing |
ASAIO J
September 2025
From the Department of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
We describe a modified Park's stitch technique incorporating systematic free margin alignment to achieve complete elimination of aortic regurgitation in patients with a left ventricular assist device. The technique involves a two-step approach: first, free margin alignment of all three cusps using single interrupted 6-0 polypropylene sutures placed at the nodules of Arantius to achieve precise coaptation, followed by conventional Park's stitch using mattress sutures with autologous pericardial pledgets for central closure. The alignment sutures remain in place to provide reinforcement.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Al Mouwasat University Hospital, Damascus University, Damascus, Syria.
Rationale: Systemic sclerosis (SS) is an immune-mediated connective disease characterized by skin fibrosis, microvascular damage, and multisystem manifestations. One of the most important processes in connective tissue disorders is vasculitis. The clinical findings can differ when the disease is presented with an antineutrophil cytoplasmic antibody.
View Article and Find Full Text PDFJ Neurosurg Case Lessons
September 2025
Department of Neurosurgery, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu Province, China.
Background: Vertebrobasilar junction (VBJ) aneurysms are frequently associated with basilar artery variations like fenestration or hypoplasia, altering hemodynamics. An interrupted aortic arch (IAA), a rare congenital malformation, may contribute to intracranial aneurysms via vascular wall defects, hemodynamic stress, and compensatory hypertension. Coexistence of IAA with cerebrovascular anomalies and VBJ aneurysms is exceptionally rare, with no prior documented cases.
View Article and Find Full Text PDFJ Vis Exp
August 2025
Department of Vascular Surgery, Rouen University Hospital.
Open surgery for abdominal aortic aneurysms requires transient interruption of blood circulation, causing ischemia-reperfusion of downstream organs. Renal, mesenteric, and splanchnic arteries may be involved. No therapy has proven effective in preventing remote lung injury caused by ischemia-reperfusion after supra-coeliac aortic clamping.
View Article and Find Full Text PDFKardiol Pol
August 2025
Department of Pediatric Cardiology and Congenital Heart Defects, Medical University of Gdansk, Gdańsk, Poland.