Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objective: Micro-nutrients are closely related to pulmonary tuberculosis (PTB). Most patients with PTB suffer from micro-nutrients deficiency. We aimed to evaluate the efficacy of micro-nutrients support on clinical therapy and chronic inflammation in patients with PTB.
Methods: We searched Pubmed, Springer link, Web of Science, Cochrane, Wan Fang and CNKI databases for randomised controlled trials (RCTs). The patients with anti-TB treatments were divided into two groups, the control group with nutritional advice or placebo, and the experimental group with micro-nutrients support for more than 2 weeks. Two reviewers conducted data extraction and quality assessment of the studies independently, and ReviewManager 5.2 software was used to input and analyse the data. The dichotomous variable was expressed in the risk ratios (RRS) and 95% CI, the continuous data were expressed in the mean difference (MD) and 95% CI, and the heterogeneity of subgroup was evaluated by I (Kerantzas and Jacobs, Jr., 2017) [2] test.
Results: A total of 13 trials (2847 participants) were included. First, micro-nutrients improved sputum smears or culture negative conversion rates (OR 0.16 0.03-0.77, 2.29; MD -2.36, -4.72~-0.01, z = 1.97). Meanwhile, micro-nutrients support increased lymphocytes and decreased leukocytes, neutrophils, CRP and ESR (MD 0.20, 0.06-0.35, z = 2.78; MD -0.42, -0.65~-0.18, z = 3.48; MD -0.66, -1.12~-0.20, z = 2.82). However it had not impact on body weight, MUAC, haemoglobin, albumin or monocytes (p > 0.05).
Conclusion: Micro-nutrients support can reduce chronic inflammation and improve sputum smears or culture conversions to contribute to anti-TB treatment.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.tube.2020.101994 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Potential Health Benefits of Dietary Tree Nut and Peanut Enrichment in Kidney Transplant Recipients-An In-Depth Narrative Review and Considerations for Future Research.
Nutrients
July 2025
Division of Nephrology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Post Box 30.001, 9700 RB Groningen, The Netherlands.
Kidney transplant recipients face a substantial burden of premature mortality and morbidity, primarily due to persistent inflammation, cardiovascular risk, and nutritional deficiencies. Traditional nutritional interventions in this population have either focused on supplementing individual nutrients-often with limited efficacy-or required comprehensive dietary overhauls that compromise patient adherence. In this narrative review, we explore the rationale for dietary nut enrichment as a feasible, multi-nutrient strategy tailored to the needs of kidney transplant recipients.
View Article and Find Full Text PDFMicrobes Mediated Nutrient Dynamics for Plant Growth Promotion: Current Research and Future Challenges.
Indian J Microbiol
June 2025
Department of Genetics, Plant Breeding and Biotechnology, Dr. Khem Singh Gill Akal College of Agriculture, Eternal University, Baru Sahib, Sirmour, 173101 Himachal Pradesh India.
On earth, soil is one of the most essential parts of nature which plays critical roles in plant growth, water flow, waste products recycling and provides habitats to various organisms. Soil is the combination of organic matter, air, water minerals, and sixteen different essential nutrient elements which are categorized into primary macronutrients, secondary macronutrients, and micronutrients. The nutrients elements present in soil either in organic forms or organic forms interchanged by the various microbial mechanisms such including fixation, chelation and solubilization.
View Article and Find Full Text PDFDietary Nucleotides Enhance Neurogenesis, Cognitive Capacity, Muscle Function, and Body Composition in Older Adults: A Randomized, Triple-Blind, Controlled Clinical Trial.
Nutrients
April 2025
Department of Physical Education and Sports, University of Valencia, 46010 Valencia, Spain.
Background/objectives: this study evaluated the differential effects of two distinct dietary nucleotide supplements, combined with spontaneous physical activity, on neuromuscular, cognitive, and metabolic adaptations in older adults.
Methods: Sixty-nine physically independent older adults (aged 60-75 years) were randomly assigned to three groups: (1) a yeast nucleotides formulation (YN) standardized in a high content of free nucleotides (>40%) rich in all macro and micro nutrients naturally occurring in yeast cell (amino acids, minerals and B-group vitamin); (2) a neuro-based formulation (NF) consisting of a blend of monophosphate nucleotides 5'; or (3) a placebo. Participants maintained their spontaneous physical activities without structured exercise during a 10-week intervention.
A Low Dietary Quality Index in a Newly Diagnosed Inflammatory Bowel Disease Cohort: Results from a Case-Control Study.
Nutrients
March 2025
IBD Department, St. Mark's Hospital and Academic Institute, London NW10 7NS, UK.
Background: Epidemiological evidence suggests a link between the risk of IBD and diet. Macro- and micro- nutrient intake, diet quality and dietary patterns may play a pivotal role in disease pathogenesis. We aimed to study the dietary intake of newly diagnosed IBD patients compared to non-IBD controls.
View Article and Find Full Text PDFLactic acid bacterial fermentation as a biotransformation strategy to enhance the bioavailability of phenolic antioxidants in fruits and vegetables: A comprehensive review.
Food Res Int
May 2025
NICM Health Research Institute, Western Sydney University, Penrith, NSW 2751, Australia; School of Science, Western Sydney University, Penrith, NSW 2751, Australia. Electronic address:
Fruits and vegetables (FVs) are rich sources of macro and micro-nutrients crucial for a healthy diet. In addition to these nutrients, FVs also contain fibre and phytochemicals known for their antioxidant properties. Despite the growing evidence of the disease-preventive role of antioxidants in FVs, their bioavailability and bioaccessibility vary significantly and have not been adequately explored.
View Article and Find Full Text PDF