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In 1998, Gold and Heffner authored a landmark review in Clinical Psychology Review on the topic of sexual addiction that concluded that sexual addiction, though increasingly popular in mental health settings, was largely based on speculation, with virtually no empirical basis. In the more than two decades since that review, empirical research around compulsive sexual behaviors (which subsumes prior research about sexual addiction) has flourished, ultimately culminating in the inclusion of a novel diagnosis of Compulsive Sexual Behavior Disorder in the eleventh edition of the World Health Organization's International Classification of Diseases. The present work details a systematic review of empirical research published between January 1st, 1995 and August 1st, 2020 related to compulsive sexual behaviors, with a specific focus on evaluating the methodologies of that literature. This review yielded 371 papers detailing 415 individual studies. In general, the present review finds that, although research related to compulsive sexual behaviors has proliferated, much of this work is characterized by simplistic methodological designs, a lack of theoretical integration, and an absence of quality measurement. Moreover, the present review finds a virtual absence of high-quality treatment-related research published within this time frame. Implications of these findings for both clinical practice and future research are discussed.
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http://dx.doi.org/10.1016/j.cpr.2020.101925 | DOI Listing |
J Sex Marital Ther
September 2025
Social Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.
The present cross-sectional study examined the chain mediating roles of spousal support and dyadic adjustment in the relationship between social media addiction and sexual functioning among 211 married women of reproductive age in Qazvin, Iran. Grounded in the Interpersonal Process Model of Intimacy, the study posited that excessive social media use displaces face-to-face interactions, thereby eroding emotional support and relational harmony, which are critical for sexual well-being. Participants completed validated measures assessing social media addiction, spousal support, dyadic adjustment, and sexual functioning through an online survey.
View Article and Find Full Text PDFObes Surg
September 2025
Department of Medical and Surgical Sciences, Internal Medicine Unit, Columbus-Gemelli Hospital, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Obesity is a globally prevalent condition associated with elevated morbidity and mortality. Metabolic and bariatric surgery offers a definitive treatment for class III (BMI > 40) obesity, achieving substantial, enduring weight loss and improving metabolic health. Despite extensive research on the physical benefits, comparatively fewer reviews investigate the psychosocial and relational changes accompanying these procedures.
View Article and Find Full Text PDFCannabis
July 2025
Department of Psychology, University of Notre Dame.
Background: With cannabis legal in nearly half of U.S. states, important concerns about the public health impact remain, particularly for states yet to legalize.
View Article and Find Full Text PDFJ Neurochem
September 2025
Grupo de NeuroGastroBioquímica, Laboratorio de Química Biológica, y Laboratorio de Bioquímica de Sistemas, Instituto de Química, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.
Investigations addressing addiction and social behaviour have found differences between males and females (men and women). Early life exposure to antibiotics (ELEA) induces addictionlike behaviours in adult male Sprague-Dawley (SD) rats, but not in females, while changing dopamine neurochemistry in females but not in males (doi: 10.3389/fphar.
View Article and Find Full Text PDFProg Neuropsychopharmacol Biol Psychiatry
August 2025
Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (IBIMA Plataforma BIONAND), Málaga, Spain; Área del Corazón, Hospital Universitario Virgen de la Victoria, Málaga, Spain; CIBER de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain;
Cocaine disrupts neurotransmitter systems and promotes neuroinflammation by activating microglia and altering cytokine signaling. The CXCL1/CXCR1 axis is an essential signaling pathway for microglial regulation, may exhibit sex-specific responses to cocaine. In this study, male and female Wistar rats were exposed to acute (5, 15, or 30 mg/kg) or repeated (15 mg/kg/day for two weeks) cocaine.
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