Archaeogenetics: What Can Ancient Genomes Tell Us about the Origin of Syphilis?

Curr Biol

Departments of Medicine and Global Health, University of Washington, Seattle, WA, USA.

Published: October 2020


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

The origin of syphilis has been hotly debated for decades. Ancient pathogen DNA may provide new evidence to redefine our understanding of this mystery, but is the mystery itself flawed in its assumptions?

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cub.2020.08.022DOI Listing

Publication Analysis

Top Keywords

archaeogenetics ancient
4
ancient genomes
4
genomes origin
4
origin syphilis?
4
syphilis? origin
4
origin syphilis
4
syphilis hotly
4
hotly debated
4
debated decades
4
decades ancient
4

Similar Publications

Background: The Slavs are a major ethnolinguistic group of Europe, yet the process that led to their formation remains disputed. As of the sixth century CE, people supposedly belonging to the Slavs populated the space between the Avar Khaganate in the Carpathian Basin, the Merovingian Frankish Empire to the West and the Balkan Peninsula to the South. Proposed theories to explain those events are, however, conceptually incompatible, as some invoke major population movements while others stress the continuity of local populations.

View Article and Find Full Text PDF

The second half of the first millennium CE in Central and Eastern Europe was accompanied by fundamental cultural and political transformations. This period of change is commonly associated with the appearance of the Slavs, which is supported by textual evidence and coincides with the emergence of similar archaeological horizons. However, so far there has been no consensus on whether this archaeological horizon spread by migration, Slavicisation or a combination of both.

View Article and Find Full Text PDF

Bone Type Selection for Human Molecular Genetic Identification of Skeletal Remains.

Genes (Basel)

July 2025

Institute of Forensic Medicine, Faculty of Medicine, University of Ljubljana, Korytkova 2, 1000 Ljubljana, Slovenia.

This review paper presents a comprehensive overview of DNA preservation in hard tissues (bones and teeth) for applications in forensic and archaeogenetic analyses. It presents bone structure, DNA location in bones and teeth, and extensive information about postmortem DNA location and preservation. Aged bones are a challenging biological material for DNA isolation due to their low DNA content, degraded DNA, and the potential presence of PCR inhibitors.

View Article and Find Full Text PDF

The transition from the Bronze Age (BA) to the Iron Age (IA) on the Northeastern Iberian Peninsula is characterized by the emergence of cremation as the main funerary practice. Cultural attributes of a group, known as the Urnfield Culture, expanded from Central Europe to Northeastern Iberia during the Final Bronze Age (FBA), from ~1300 to ~850 cal BCE. Various hypotheses on the group's emergence exist, but cremations hinder DNA preservation.

View Article and Find Full Text PDF

In recent years, sediments from cave environments have provided invaluable insights into ancient hominids, as well as past fauna and flora. Unfortunately, however, sediments are not always collected during excavation. In this study, we analyzed an overlooked but abundant resource in archaeological collections - sediments adhered to bone.

View Article and Find Full Text PDF