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Background: The Prechtl General Movement Assessment (GMA) predicts various neurological and developmental disorders while also documenting therapeutic effects.
Aims: To describe the temporal organization of fidgety general movements in infants with mild to moderate postural asymmetries and/or tonus regulation problems, and to analyze to what extent the temporal organization of fidgety movements will change after physiotherapy.
Study Design: Repeated measure design.
Participants: Twelve infants (five females) with mild to moderate postural asymmetries and/or tonus regulation problems were admitted for an early intervention program. The gestational age ranged from 27 to 40 weeks (Median, 36 weeks; nine infants born preterm) with birth weights ranging from 740 g to 3500 g (Median, 2590 g).
Measures: Fidgety movements and their temporal organization were measured using the Prechtl GMA at 9 to 19 weeks post term age (Median, 14 weeks) before and after an early motor training procedure. The movements of one of the infants were analysed using a computer-based approach, measuring the mean and standard deviation of quantity of motion, height of motion and width of motion.
Results: Seven infants had sporadic fidgety movements, and five had intermittent fidgety movements. None had continual fidgety movements before the intervention was initiated. After intervention, the temporal organization of fidgety movements increased in all infants. The observations of these movements were supported by computer-based analysis.
Conclusion: The study indicates that early intervention increases the temporal organization of fidgety movements in infants with postural asymmetries and/or tonus regulation problems. The clinical significance of this finding needs to be further evaluated.
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http://dx.doi.org/10.1016/j.earlhumdev.2020.105197 | DOI Listing |
Medicine (Baltimore)
August 2025
Xi'an Daxing Hospital, Xi'an, China.
Background: This meta-analysis assessed the diagnostic value of writhing and fidgety general movements (GMs) for predicting cerebral palsy.
Methods: We searched PubMed, EMBASE, Cochrane Library, CINAHL, and Web of Science for cohort or case-control studies evaluating GMs. We calculated the superiority index (S), sensitivity, specificity, likelihood ratios, diagnostic odds ratio (DOR), and area under the curve (AUC) using STATA.
JAMA Netw Open
July 2025
Monash Newborn, Monash Children's Hospital, Melbourne, Australia.
Importance: Umbilical cord blood-derived cells (UCBCs) are increasingly being evaluated for neuroprotective properties in perinatal brain injury.
Objective: To report early neurodevelopmental outcomes of extremely preterm infants who received autologous UCBCs in the CORD-SaFe study.
Design, Setting, And Participants: This study reports early follow-up on the preplanned secondary aims of a phase 1 safety and feasibility nonrandomized clinical trial conducted between May 2021 and November 2023, with early follow-up completed in August 2024.
J Pediatr
October 2025
The Kids Research Institute Australia, Perth, Western Australia; Perth Children's Hospital, Perth, Western Australia; UWA Medical School, The University of Western Australia, Perth, Western Australia.
Objective: To describe the infant and maternal characteristics of the Early Moves cohort and to assess representativeness to the general population, and to evaluate the implementation fidelity of an application-based collection of General Movement Assessment (GMA) videos at writhing and fidgety age.
Study Design: Prospective observational study. Mothers who had recently delivered or were enrolled to deliver at maternity hospitals in Perth, Western Australia, were recruited from November 2019 to December 2023.
Dev Med Child Neurol
June 2025
Queensland Cerebral Palsy and Rehabilitation Research Centre, Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.
Aim: To determine reproducibility and diagnostic accuracy of screening tools for neuromotor concerns indicative of cerebral palsy (CP) at 18 months corrected age by using the General Movements Assessment (GMA) and/or Hammersmith Infant Neurological Examination (HINE) in West Bengal, India.
Method: This prospective substudy tested psychometrics of screening tools nested within an overarching randomized control trial. A total of 785 infants with birth/infant-detectable risk factors, aged 12 to 40 weeks corrected age (n = 422 male, mean corrected age 22.
Children (Basel)
May 2025
Faculty of Health Sciences, HM Hospitals, University Camilo José Cela, Urb. Villafranca del Castillo, Villanueva de la Cañada, 49, 28692 Madrid, Spain.
The General Movements Assessment provides early insight into motor development's range of motion; however, its relationship with joint kinematics, such as hip abduction range of motion, remains underexplored. This study analyzed hip abduction kinematics during General Movements, evaluating potential sex differences and variations in movement patterns (Fidgety vs. Writhing), and aimed to provide quantitative data that complement qualitative pediatric assessments.
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