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Background: Network analysis has become popular among PTSD researchers for studying causal structure or interrelationships among symptoms. However, some have noted that results do not seem to be consistent across studies. Preliminary evidence suggests that trauma type may be one source of variability.
Methods: The current study sought to examine the PTSD networks of veterans with combat versus non-combat index trauma. Participants included 944 veterans who completed the PTSD Checklist for DSM-5 at intake at two VA PTSD clinics.
Results: There were many similarities between the combat and non-combat trauma networks, including strong edges between symptoms that were theoretically related or similar (e.g., avoidance) and negative emotion being a highly central symptom. However, correlations of edge weights (0.509) and node centrality (0.418) across networks suggested moderate correspondence, and there appeared to be some differences associated with certain symptoms. Detachment was relatively more central and the connections of negative emotion with blame and lack of positive emotion with reckless behavior were stronger for veterans with combat-related index trauma.
Limitations: The data were cross-sectional, which limits the ability to infer directional relationships between symptoms. In addition, the sample was likely not large enough to directly test for differences between networks via network comparison tests.
Conclusions: Although there were many similarities, results also suggested some variability in PTSD networks associated with combat versus non-combat index trauma that could have implications for conceptualizing and treating PTSD among veterans.
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http://dx.doi.org/10.1016/j.jad.2020.08.027 | DOI Listing |
Brain Behav
September 2025
Pontificia Universidad Javeriana, Facultad De Ciencias, Departamento de Biología, Biología de Plantas y Sistemas Productivos, Bogotá, Colombia.
Introduction: The study explores shared genetic architecture among major psychiatric disorders-major depressive disorder, bipolar disorder, schizophrenia, and post-traumatic stress disorder-emphasizing their overlapping molecular pathways. Using public datasets, we identified shared genes and examined their functional implications through protein-protein interaction (PPI) networks and gene set enrichment analysis (GSEA).
Methods: Genes associated with each disorder were identified through the NCBI Gene database.
Psychol Psychother
September 2025
Center for Linguistics and Applied Linguistics/School of English Education, Guangdong University of Foreign Studies, Guangzhou, China.
Objectives: This study used a network approach to examine gender differences in adolescents regarding unresolved attachment styles, COVID-19 PTSD symptoms, comorbid psychiatric symptoms, and contamination fear. The rationale for the study stems from the suggestion that parents' relationships with adolescents (i.e.
View Article and Find Full Text PDFFront Psychiatry
August 2025
Specialty of Psychiatry, Sydney Medical School, University of Sydney, Westmead, NSW, Australia.
Background: Post-traumatic stress disorder (PTSD) is a debilitating condition affecting 3.9% of the global population, with refugee populations experiencing particularly high prevalence rates (23-42%). Cognitive control deficits are a core feature of PTSD and a significant factor in treatment resistance, which affects 25-60% of cases.
View Article and Find Full Text PDFDepress Anxiety
September 2025
Nursing Department, Zhongnan Hospital of Wuhan University, 169, East-Lake Road, Wuhan 430071, China.
Postpartum depression (PPD) and postpartum post-traumatic stress disorder (PP-PTSD) are prevalent among women. However, the specific symptoms that serve as bridges remain unknown between these two disorders. The objective of this study is to establish a symptom network model for PPD and PP-PTSD and investigate the bridge symptoms and their interrelationships in cases of comorbid PPD and PP-PTSD.
View Article and Find Full Text PDFInt J Soc Psychiatry
September 2025
Shanghai Key Laboratory of Mental Health and Psychological Crisis Intervention, Affiliated Mental Health Center (ECNU), Positive Education China Academy (PECA) of Han-Jing Institute for Studies in Classics, Juzhe Xi's Master Workroom of Shanghai School Mental Health Service, School of Psychology and
Background: Prior research on rumination and resilience in trauma contexts has primarily utilized traditional statistical methods, single-sample designs, and community-based participants. As a result, symptom-level interaction patterns and network structures across varying risk levels remain unclear. This study aims to address these limitations by comparing the network structures of rumination and resilience among adolescents exposed to a public health crisis, both with and without PTSD.
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