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A rapidly expanding new field of lung research has been produced by the emergence of culture-independent next-generation sequencing technologies. While pulmonary microbiome research lags behind the exploration of the microbiome in other organ systems, the field is maturing and has recently produced multiple exciting discoveries. In this mini-review, we will explore recent advances in our understanding of the lung microbiome and the gut-lung axis from an ecological perspective.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642895 | PMC |
http://dx.doi.org/10.1152/ajplung.00360.2020 | DOI Listing |
Arterioscler Thromb Vasc Biol
September 2025
Faculty of Medicine, Department of Physiology, University of Iceland, Reykjavik (G.K.).
Biological sex influences the life course development of blood pressure, systemic arterial hypertension, and hypertension-associated complications through neural, hormonal, renal, and epigenetic mechanisms. Sex hormones influence blood pressure regulation through interaction with several main regulatory systems, including the autonomic nervous system, the renin-angiotensin-aldosterone system, endothelin, and renal mechanisms. The modulation of vascular function by sex hormones varies over the lifespan.
View Article and Find Full Text PDFPhysiol Plant
September 2025
State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Agriculture, South China Agricultural University, Guangzhou, China.
The rice root system mediates nutrient uptake while adapting to tillage, management, and environmental changes. While optimized nitrogen (N) supply is known to enhance 2-acetyl-1-pyrroline (2-AP) biosynthesis in fragrant rice, the underlying mechanisms linking nitrogen availability, root development, and their combined effects on physiological processes and aroma formation remain unclear. To address this knowledge gap, we conducted a pot experiment employing two fragrant rice cultivars (Huahangxiangyinzhen and Qingxiangyou19xiang) under three nitrogen regimes (0, 1.
View Article and Find Full Text PDFNanoscale Horiz
September 2025
Department of Physics, University of Science and Technology of China, 230026 Hefei, Anhui, China.
Surface photocatalysis holds significant promise for converting solar energy into chemical fuels and addressing environmental challenges. While calculations provide critical insights into the thermodynamic and kinetic aspects of catalytic reactions, applying these methods to surface photocatalysis remains challenging. In this work, we discuss the key challenges that need to be addressed when using calculations to understand surface photocatalytic processes, the reasons behind these challenges, and the potential directions and opportunities for overcoming them in the future.
View Article and Find Full Text PDFAdv Wound Care (New Rochelle)
September 2025
Beijing Laboratory of Biomedical Materials, State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, PR China.
Wound healing is a complex, tightly regulated process involving a range of enzymes, growth factors, and cytokines that coordinate cellular activities essential for tissue repair and wound closure. However, in cases of extensive or severe injury, the intrinsic repair mechanisms are often insufficient, underscoring the need for advanced therapeutic strategies to accelerate healing and minimize scar formation. Electrically conductive hydrogels (ECHs), combining the advantageous properties of hydrogels with the physiological and electrochemical characteristics of conductive materials, present a safer and more convenient alternative to traditional electrode-based electrical stimulation (ES) for treating chronic and nonhealing wounds.
View Article and Find Full Text PDFChembiochem
September 2025
Department of Chemistry, University of Florida, Gainesville, FL, 32611, USA.
Mechanoglycobiology has emerged as a rapidly expanding interdisciplinary field that involves chemistry, biology, and engineering. Despite the great advancements in this field, in-depth investigation of mechanoglycobiology remains challenging due to the complex nature of glycans and cell glycocalyx, as well as the difficulty to mechanically target these biomolecules. To address the issues, novel methods and models have been established to facilitate the investigation of glycan-mediated mechanosensing and mechanotransduction.
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