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The aim of this paper is to review and systematize the current state of knowledge on glycol metabolism in cattle. Glycerol, derived from biodiesel production, must be purified in order to be a useful product for feeding livestock. The use of glycerol in the feeding of ruminants can be justified for several reasons: (i) it is a source of energy in the ration, (ii) it is a glucogenic precursor, and (iii) it may have an effect on milk composition. The high energy value of glycerol provides the opportunity to use this raw material as a partial grain substitute in cattle feed rations. Dietary supplementation of glycerol is associated with increased propionate, butyrate, valerate, and isovalerate concentrations in the rumen. Glycerol can be used at up to 10%-15% of the dietary dry matter (DM) and is well-established as a treatment for ketosis in cows. Glycerol increases plasma glucose and may reduce non-esterified fatty acids and β-hydroxybutyrate levels. The use of glycerol does not have a clear effect on DM intake, milk yield, or milk composition. However, some authors have reported an increase in milk yield after glycerol supplementation associated with decreased milk fat concentration. It is also possible that the concentration in the milk of odd-chain fatty acids and -9, -11 conjugated linoleic acid may increase after glycerol application.
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http://dx.doi.org/10.3390/ani10081379 | DOI Listing |
FEBS Open Bio
September 2025
Department of Biochemistry, State University of Maringá, Maringá, Brazil.
Epigallocatechin-3-gallate (EGCG), the main catechin in green tea, is associated with antidiabetic and anti-obesity effects, although its acute hepatic actions remain unclear. We investigated short-term effects of EGCG (10-500 μm) using isolated perfused rat livers and complementary assays in mitochondrial, microsomal, and cytosolic fractions. EGCG markedly inhibited gluconeogenesis from lactate (up to 52%), glycerol (33%), and alanine (47%), while it stimulated glycolysis, glycogenolysis, and oleic acid oxidation (+42% total ketone bodies).
View Article and Find Full Text PDFPathol Res Pract
September 2025
Adiyaman University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Adiyaman, Turkey. Electronic address:
Aim: This study aims to evaluate the effects of bupivacaine on acute kidney injury (AKI) through kidney function parameters and cardiac tissue damage via TRPM2, HSP70, TLR4, NF-κB, and TNF-α biomarkers.
Material And Method: Male Wistar albino rats were divided into 4 groups, with seven rats in each group: Control group, AKI group (kidney damage induced by glycerol), AKI + L group (group treated with bupivacaine), and L group (group treated with bupivacaine alone). At the end of the experiment, kidney and heart tissues were collected for histological analysis, and serum samples were taken for biochemical analysis.
Int J Biol Macromol
September 2025
Planta Piloto de Procesos Industriales Microbiológicos (PROIMI-CONICET), Laboratorio de Biomateriales y Bioprocesos, Av. Belgrano y Pasaje Caseros, SM de Tucumán, 4000, Tucumán. R, Argentina; Universidad Nacional de Tucumán, Facultad de Bioquímica, Química y Farmacia. Laboratorio de Bioproceso
This study explores the use of plant-derived polysaccharides to develop bio-based films for food-packaging applications. A film-forming solution composed of Prosopis nigra biopolymer (PN-B), carboxymethyl cellulose (CMC), and glycerol was optimized by central composite design (CCD), resulting in two formulations: P1 and P11. The films were subsequently functionalized with silver nanoparticles (AgNPs) synthesized via chemical and biological routes.
View Article and Find Full Text PDFCarbohydr Polym
November 2025
Unilever Research & Development Port Sunlight, Bebington CH63 3JW, UK.
Kappa carrageenan (KC), a sulfated polysaccharide derived from red seaweed, exhibits distinct gelation properties that are influenced by ionic strength and thermal conditions. While its behavior in aqueous media is well-established, understanding KC's gelation mechanisms in non-aqueous solvents (like glycerol) remains limited. This study investigates the conformational and rheological properties of kappa carrageenan in glycerol, focusing on the effects of sodium salts (NaCl, NaHPO, NaPO) at varying concentrations and preparation temperatures (60 °C and 80 °C).
View Article and Find Full Text PDFFood Chem
August 2025
Food Engineering and Technology Department, Institute of Chemical Technology, Matunga, Mumbai, India.
Coextraction of Citrullus lanatus seeds and Citrus aurantium peels (1:1, w/w), two food processing wastes, was performed using supercritical carbon dioxide (scCO) (345 bar|57 °C|178 min) and pet ether solvents. The major objective of the study was to valorize two fruit processing wastes to obtain a bioactive coextract using a green scCO extraction process and further incorporate it into wax-based composite oleofoams. The scCO coextraction resulted in better extraction of bioactive compounds such as d-limonene and polyunsaturated fatty acids due to the absence of light and lower temperature of extraction, compared to pet ether.
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