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Background: To provide effective rehabilitation in the early post-injury stage, a novel robotic rehabilitation platform is proposed, which provides full-body arm-leg rehabilitation via belt actuation to severely disabled patients who are restricted to bed rest.
Objective: To design and technically evaluate the preliminary development of the rehabilitation platform, with focus on the generation of various leg movements.
Methods: Two computer models were developed by importing the components from SolidWorks into Simscape Multibody in MATLAB. This allowed simulation of various stepping movements in supine-lying and side-lying positions. Two belt-actuated test rigs were manufactured and automatic control programs were developed in TIA Portal. Finally, the functionality of the test rigs was technically evaluated.
Results: Computer simulation yielded target positions for the generation of various stepping movements in the experimental platforms. The control system enabled the two-drive test rig to provide three modes of stepping in a supine position. In addition, the four-drive test rig produced walking-like stepping in a side-lying position.
Conclusions: This work confirmed the feasibility of the mechanical development and control system of the test rigs, which are deemed applicable for further development of the overall novel robotic rehabilitation platform.
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http://dx.doi.org/10.3233/THC-202392 | DOI Listing |
Nat Aging
September 2025
Aging Biomarker Consortium (ABC), Beijing, China.
The global surge in the population of people 60 years and older, including that in China, challenges healthcare systems with rising age-related diseases. To address this demographic change, the Aging Biomarker Consortium (ABC) has launched the X-Age Project to develop a comprehensive aging evaluation system tailored to the Chinese population. Our goal is to identify robust biomarkers and construct composite aging clocks that capture biological age, defined as an individual's physiological and molecular state, across diverse Chinese cohorts.
View Article and Find Full Text PDFMed Eng Phys
October 2025
Mechatronics Engineering Department, Sakarya University of Applied Sciences, Serdivan, Sakarya, 54600, Sakarya, Turkey; Systems Engineering Department, Military Technological College, Al Matar, Muscat, 111, Muscat, Oman. Electronic address:
Balance is a critical component of daily activities and overall quality of life. This study aims to develop a cost-effective exercise system for the rehabilitation of balance disorders by combining a sensor module with target-oriented video games. The system, designed using a microcontroller-controlled sensor module and Unity game engine, features a game component that provides visual feedback and is synchronized with the platform movements.
View Article and Find Full Text PDFDiscov Nano
September 2025
Department of Rehabilitation Medicine, Rehabilitation Medical Center, Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Immunoelectron Microscopy (IEM) is a technique that combines specific immunolabeling with high-resolution electron microscopic imaging to achieve precise spatial localization of biomolecules at the subcellular scale (< 10 nm) by using high-electron-density markers such as colloidal gold and quantum dots. As a core tool for analyzing the distribution of proteins, organelle interactions, and localization of disease pathology markers, it has irreplaceable value, especially in synapse research, pathogen-host interaction mechanism, and tumor microenvironment analysis. According to the differences in labeling sequence and sample processing, the IEM technology system can be divided into two categories: the first is pre-embedding labeling, which optimizes the labeling efficiency through the pre-exposure of antigenic epitopes and is especially suitable for the detection of low-abundance and sensitive antigens; the second is post-embedding labeling, which relies on the low-temperature resin embedding (e.
View Article and Find Full Text PDFDisabil Rehabil Assist Technol
September 2025
International Communication College, Jilin International Studies University, Changchun, Jilin, China.
Background: Conventional automated writing evaluation systems typically provide insufficient support for students with special needs, especially in tonal language acquisition such as Chinese, primarily because of rigid feedback mechanisms and limited customisation.
Objective: This research develops context-aware Hierarchical AI Tutor for Writing Enhancement(CHATWELL), an intelligent tutoring platform that incorporates optimised large language models to deliver instantaneous, customised, and multi-dimensional writing assistance for Chinese language learners, with special consideration for those with cognitive learning barriers.
Methods: CHATWELL employs a hierarchical AI framework with a four-tier feedback mechanism designed to accommodate diverse learning needs.
J Multidiscip Healthc
September 2025
School of Nursing and Health, Henan University, Kaifeng, Henan, 475004, People's Republic of China.
Objective: To explore the transitional care experiences of patients with heart failure (HF) in China, identifying the challenges they face and their needs during the transition from hospital to home.
Methods: A qualitative approach was employed, recruiting 18 participants from a tertiary hospital cardiology department between June and October 2023. Data were collected through semi-structured interviews and analysed using thematic analysis.