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Bitter melon ( L.) is a fruit that brings health benefits to consumers because the fruit is rich in bioactive compounds. In this work, a combination of low-temperature convective drying and microwave radiation was used to dehydrate sliced bitter melon. One-factor-at-a-time design was performed to evaluate the influence of microwave power density (1.5, 3.0, 4.5 W/g), drying temperatures (20, 25, and 30°C), and air velocity (1.0, 1.2 and 1.4 m/s) on the change of moisture content, nutrient levels (vitamin C and total phenolics), and the antioxidant activities (DPPH and FRAP assays) of the bitter melon. The obtained results showed that all investigated factors affected the rate of moisture removal. Microwave power density output and air-drying temperature strongly participated in the retention of nutrients. In this study, the drying process was driven by both heat and mass transfer processes, so the increase of air velocity prolonged the drying time causing more loss of nutrient levels and antioxidant activities. It was found that DPPH free radical scavenging ability directly correlated with total phenolic content, but the ferric-reducing antioxidant power was related to the presence of reductants including phenolic compounds, vitamin C, and other phytochemicals in bitter melons. This work determined that microwave power density and the air-drying temperature are the main two factors that should be used for further investigations.
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http://dx.doi.org/10.1002/fsn3.1676 | DOI Listing |
Microorganisms
August 2025
Food Animal Environmental Systems Research Unit, Agricultural Research Service, U.S. Department of Agriculture, Bowling Green, KY 42101, USA.
We utilized silver nanoparticles synthesized from bitter melon () extracts for testing against the common agricultural pathogen . The synthesized nanoparticles were characterized and confirmed as silver nanoparticles by using ultraviolet spectroscopy, Fourier transform infrared spectroscopy, and scanning electron microscopy analysis. The results show that AgNPs were effective against ATCC25922 strain.
View Article and Find Full Text PDFPlant Physiol Biochem
August 2025
Jiangsu Key Laboratory for Horticultural Crop Genetic Improvement, Institute of Vegetable Crops, Jiangsu Academy of Agricultural Sciences, Nanjing, 210014, China. Electronic address:
Powdery mildew (PM) is one of the most serious diseases in balsam pear. MLO (Mildew Resistance Locus O) is a key factor in the response of plants to PM infection, but its regulation mechanism remains poorly understood. In this study, overexpression of McMLO7b (MLO7b in Momordica charantia L) was found to potentially enhance Arabidopsis susceptibility to PM, confirming that McMLO7b acts as a susceptibility factor during PM infection.
View Article and Find Full Text PDF3 Biotech
September 2025
Division of Crop Protection, ICAR - National Research Centre for Banana (NRCB), Tiruchirappalli, India.
Unlabelled: Mosaic disease, caused by whitefly-transmitted begomoviruses, significantly threatens bitter gourd cultivation in India. This study identified and characterized the complete genome of coccinia mosaic Virudhunagar virus (CoMViV) from symptomatic bitter gourd samples collected in Oddanchatram block of Dindigul district, Tamil Nadu, using rolling circle amplification and sequencing. A loop-mediated isothermal amplification (LAMP) protocol was optimized by targeting regions of the CoMViV AV1 and AV2 genes.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
August 2025
Faculty of Pharmacy and Medical Sciences, University of Petra, Amman, Jordan.
Objective: This study investigates the pharmacokinetic interactions and anticancer potential for rosuvastatin in combination with Momordica charantia (M. charantia) extract through both in vitro and in vivo models.
Methods: A validated high-performance liquid chromatography (HPLC) method (R² = 0.
Nutrients
July 2025
Department III of Functional Sciences, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Plant supplements are frequently used by diabetes mellitus (DM) patients in the management of their disease. The present study aimed to identify the prevalence of plant supplement use in DM patients from Romania and to evaluate patients' practices, profiles, and beliefs regarding plant supplements and the impact of their use on glycemic control. A cross-sectional online survey was conducted among Romanian diabetic patients.
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