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http://dx.doi.org/10.1111/ajd.13396 | DOI Listing |
Clin Exp Dermatol
September 2025
Department of Dermatology, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.
Ital J Pediatr
September 2025
Pediatric Unit, Meyer Children's Hospital IRCCS, Florence, Italy.
Background: Staphylococcal-scalded skin syndrome (SSSS) is a potentially life-threatening disorder characterized by superficial skin blistering caused by exfoliative toxins produced by Staphylococcus aureus. This study aimed to investigate SSSS in a cohort of children admitted at a tertiary pediatric hospital in Italy.
Methods: Patients discharged with the diagnosis of staphylococcal infection and of SSSS between January 2010 and March 2023 were retrospectively identified using ICD-9-CM codes (695.
JAAD Case Rep
September 2025
Faculty of Medicine, University of Iceland, Reykjavík, Iceland.
JNMA J Nepal Med Assoc
October 2024
Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal.
Staphylococcal Scalded Skin Syndrome (SSSS) is a severe exfoliative skin condition primarily affecting children, caused by the toxins produced by This case report describes the clinical presentation, diagnostic challenges, and successful management of SSSS complicated by Methicillin-Resistant (MRSA) in a pediatric patient. A pediatric patient presented with a two-week history of pruritic vesiculobullous eruptions that progressively worsened. Despite initial treatments with various topical and oral medications including steroid and antibiotic ointments, the lesions continued to progress.
View Article and Find Full Text PDFPediatr Dermatol
July 2025
Department of Dermatology, University of Utah, Salt Lake City, Utah, USA.
Background: Significant gaps exist in the literature regarding the work-up and management of staphylococcal scalded skin syndrome (SSSS). These include (a) the utility of ancillary testing in improving diagnostic accuracy and informing patient care, and (b) appropriate management strategies for antibiotics, fluids, and skin care. Moreover, no systematic review to date has focused on non-neonatal pediatric SSSS to provide a comprehensive analysis of the literature.
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