Developing a SARS-CoV-2 Vaccine at Warp Speed.

JAMA

Division of Infectious Diseases, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Published: August 2020


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1001/jama.2020.12190DOI Listing

Publication Analysis

Top Keywords

developing sars-cov-2
4
sars-cov-2 vaccine
4
vaccine warp
4
warp speed
4
developing
1
vaccine
1
warp
1
speed
1

Similar Publications

Background: The interprofessional educational curriculum for patient and personnel safety is of critical importance, especially in the context of the COVID-19 pandemic, to prepare junior multiprofessional teams for emergency settings.

Objective: This study aimed to evaluate the effectiveness of an innovative interprofessional educational curriculum that integrated medical movies, massive open online courses (MOOCs), and 3D computer-based or virtual reality (VR) simulation-based interprofessional education (SimBIE) with team co-debriefing to enhance interprofessional collaboration and team performance using Team Strategies and Tools to Enhance Performance and Patient Safety (TeamSTEPPS). This study addressed 3 key questions.

View Article and Find Full Text PDF

Feasibility, Acceptability, and Preliminary Outcomes of a Mobile Adaptation of a Relational Savoring Intervention to Prevent Loneliness in College Students: Mixed Methods Pilot Study.

JMIR Form Res

September 2025

Department of Psychological Science, School of Social Ecology, University of California, Irvine, 4201 Social and Behavioral Sciences Gateway, Irvine, CA, 92697, United States, 1 203-887-8857.

Background: Rates of loneliness have risen sharply since the onset of the COVID-19 pandemic, largely due to disruptions in social relationships and daily routines, with college students experiencing some of the greatest increases. While prevention programs targeting loneliness have been developed, their success has been limited. One promising approach may lie in enhancing the quality of existing relationships rather than simply increasing social interactions during periods of acute loneliness.

View Article and Find Full Text PDF

Coronavirus, a large family of positive-sense RNA viruses, are responsible for both mild and severe respiratory illnesses, ranging from the common cold to life-threatening conditions. Despite significant advances in vaccine and antiviral development, the high mutability of human coronaviruses (HCoVs), such as SARS-CoV-2, presents a major challenge in treating these infections. Effective, broad-spectrum antiviral drugs are urgently needed to address both current and future HCoV outbreaks.

View Article and Find Full Text PDF

Understanding acute infectious disease dynamics at individual and population levels is critical for informing public health preparedness and response. Serological assays, which measure a range of biomarkers relating to humoral immunity, can provide a valuable window into immune responses generated by past infections and vaccinations. However, traditional methods for interpreting serological data, such as binary seropositivity and seroconversion thresholds, often rely on heuristics that fail to account for individual variability in antibody kinetics and timing of infection, potentially leading to biased estimates of infection rates and post-exposure immune responses.

View Article and Find Full Text PDF

While the COVID-19 pandemic has significantly impacted mental health, limited information exists on the relationship between COVID-19 infection and mental health disorders in children and adolescents. This study explored the association between COVID-19 infection, infection severity, and the risk of depression and anxiety among school-aged youth. Data from the 2019-2021 Utah All Payers Claims Database (APCD) was used to identify children and adolescents (aged 6-15 years in 2019) covered by private insurance or Medicaid.

View Article and Find Full Text PDF