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http://dx.doi.org/10.1007/s40122-020-00179-z | DOI Listing |
J Mater Chem B
September 2025
Department of Chemistry, Indian Institute of Technology Ropar, Rupnagar, Punjab 140001, India.
The unregulated use and improper disposal of active pharmaceutical ingredients (APIs), particularly phenylbutazone (PBZ), are contaminating water resources and posing serious risks to the food chain. PBZ is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for treating pain and fever in animals, and its persistence in the environment due to inadequate waste management has become a cause of concern. To address this, we report the fabrication of benzimidazole-based self-assembled nanomicelles (R2 NMs) for selective detection and removal of PBZ.
View Article and Find Full Text PDFEur J Case Rep Intern Med
August 2025
Internal Medicine, University of California, Riverside School of Medicine, Riverside, USA.
Introduction: Pulmonary embolism (PE) is a life-threatening condition with well-defined management strategies; however, the presence of a clot-in-transit (CIT)-a mobile thrombus within the right heart-introduces a uniquely high-risk scenario associated with a significantly elevated mortality rate. While several therapeutic approaches are available-including anticoagulation, systemic thrombolysis, surgical embolectomy, and catheter-directed therapies-there is no established consensus on a superior treatment modality. Catheter-based mechanical thrombectomy has emerged as a promising, minimally invasive alternative that mitigates the bleeding risks of systemic thrombolysis and the invasiveness of surgery.
View Article and Find Full Text PDFEur J Case Rep Intern Med
August 2025
Department of Gastroenterology, Staten Island University Hospital - Northwell Health, Staten Island, USA.
Unlabelled: Colorectal mucoceles are rare mucinous cysts arising in the gastrointestinal tract and presenting diagnostic and therapeutic challenges. We report the first successful treatment of an extraluminal colorectal mucocele using a lumen-apposing metal stent (LAMS). A 65-year-old male with a known medical history of diverticulitis treated with a partial colectomy presented with constipation and low back pain.
View Article and Find Full Text PDFCureus
August 2025
Gastroenterology and Hepatology Division of the Department of Internal Medicine, University of Michigan, Ann Arbor, USA.
Strictures are common in inflammatory bowel disease (IBD) and are managed medically and endoscopically, if feasible, due to the risk of surgical complications. While endoscopic balloon dilation (EBD) is often successful, the need for repeat dilation and subsequent surgery is common. Endoscopic stricturotomy (ESt) has gained popularity but has been limited by frequent post-procedural bleeding.
View Article and Find Full Text PDFEur J Orthop Surg Traumatol
September 2025
University of Leeds, Leeds, United Kingdom.
Introduction: This study aimed to evaluate the health perception of quality of life and function in patients with segmental bone defects (SBD) of the femur or tibia treated with the Induced Membrane Technique (IMT) and achieved bone healing and infection control.
Methods: This cross-sectional cohort study was conducted at a single referral center. Patients with infected SBD of the femur or tibia treated with IMT were included if they had at least 12 months of bone healing and no evidence of infection.