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Purpose: Evaluate macular features on preoperative ocular coherence tomography as indicators of postoperative visual gain following vitrectomy for epiretinal membrane (ERM).
Methods: A retrospective chart review of 66 eyes that underwent vitrectomy with membrane and internal limiting membrane peeling for symptomatic ERM. Inclusion criteria required a pre-op visual acuity of at least 20/200 and minimum follow-up of 1 year. In addition, 31 of these eyes with complete 5-line raster pre-op ocular coherence tomography had segmentation analysis which included noncentral ERM to inner nuclear layer and ERM to outer plexiform layer measurements.
Results: Eyes with "domed" pre-op macular contour had a mean preoperative acuity of 20/70 and gained a mean 2.4 lines at one year, compared with those with "flat" or "depressed" macular contour, having a 20/60 mean preoperative acuity and 0.6 lines gained (P = 0.02). Changes for other ocular coherence tomography features examined were not statistically significant. Paracentral ERM to inner nuclear layer measurements had moderate correlation, whereas paracentral ERM to outer plexiform layer measurements had weak correlation with gain in visual acuity.
Conclusion: An inner macular-domed contour in eyes with ERM predicted better visual gain after vitrectomy with ERM and internal limiting membrane peeling compared with a flat or depressed contour.
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http://dx.doi.org/10.1097/IAE.0000000000002869 | DOI Listing |
Transl Vis Sci Technol
August 2025
Ophthalmology and Visual Sciences, The University of Alabama at Birmingham, Heersink School of Medicine, Birmingham, AL, USA.
Purpose: To allow exploration of xanthophyll carotenoids in vision and age-related macular degeneration progression using two-wavelength autofluorescence imaging for macular pigment optical density (MPOD), we developed tools for automatically centering and classifying the MPOD distribution pattern.
Methods: A subset of the ALSTAR2 baseline cohort (NCT04112667) and 44 eyes of adults aged 20 to 30 years with healthy maculas were imaged with optical coherence tomography and two-wavelength autofluorescence (MPOD module, Heidelberg Engineering). Images underwent a quality review.
Eur J Ophthalmol
August 2025
School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
PurposeThe aim of this study is to evaluate the efficacy of neurovisual rehabilitation using the AvDesk training system (Linari Medical, Pisa, Italy) in patients with geographic atrophy (GA) due to age-related macular degeneration (AMD) in their eye with better visual acuity.MethodsThis study employed a prospective, observational, single-centre case series design. All patients underwent neurovisual rehabilitation using an AvDesk device.
View Article and Find Full Text PDFSci Rep
July 2025
Department of Ophthalmology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
This study aimed to explore the characteristics of the natural Preferred Retinal Locus (PRL) in eyes with different macular lesions. In this retrospective study, 37 patients (39 eyes) suffered from macular diseases (MD) were included, and the following data were collected: best corrected visual acuity (BCVA), mean sensitivity of macular area in 10 deg diameter (MS), bivariate contour ellipse area (63% BCEA and 95% BCEA), fixation stability, and fundus images and sectional images of the fovea. A natural PRL did not develop in 10 eyes with macular disease.
View Article and Find Full Text PDFOphthalmol Retina
July 2025
Casey Eye Institute, Oregon Health & Science University, Portland, Oregon. Electronic address:
Purpose: This study presents 2 methods of en face visualization enabled by ultra-widefield (UWF) OCT, which provide topographic information of retinopathy of prematurity (ROP) without requiring direct visualization of cross-sectional scans.
Design: Evaluation of diagnostic technology.
Subjects: Infants undergoing ROP screening at Oregon Health Science University between June 2023 and October 2024, who consented to research imaging.
Transl Vis Sci Technol
June 2025
UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA, USA.
Purpose: Quantitative evaluation of choroidal curvature including choroidal inner boundary (CIB) and choroidal outer boundary (COB) and report a comparison between healthy and diseased eyes.
Methods: This retrospective study was conducted on 97 eyes of 97 patients. Eyes were divided into three groups: central serous chorioretinopathy (CSCR), dry age-related macular degeneration (AMD), and healthy eyes.