98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256902 | PMC |
http://dx.doi.org/10.14639/0392-100X-N0267 | DOI Listing |
Korean J Anesthesiol
September 2025
Department of Anesthesiology and Pain Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan 15588, the Republic of Korea.
Background: Despite the well-known effects of elevated bilirubin in neonates, its neurotoxic potential in adults remains uncertain. In perioperative and hepatic disease contexts, transient bilirubin elevations are common; however, their direct contribution to cognitive dysfunction has not been clearly established. This study aimed to determine whether transient bilirubin elevation alone can impair cognition and disrupt blood-brain barrier (BBB) function in adult zebrafish, and to compare these effects with those of liver injury.
View Article and Find Full Text PDFDisabil Rehabil
September 2025
Occupational Performance Network, Sydney, Australia.
Purpose: Initial studies identified the Perceive, Recall, Plan and Perform Assessment (PRPP-A) as a cognitive assessment with potential for culturally safe use with Aboriginal and Torres Strait Islander peoples with neurocognitive impairments in the Northern Territory of Australia. This study examines construct and concurrent validity of the PRPP-A.
Methods: Data were collected from a medical record review.
Rev Esp Anestesiol Reanim (Engl Ed)
September 2025
Department of Neurology, Xuzhou Central Hospital, Xuzhou, China. Electronic address:
Objective: This study aims to investigate the effects of anaesthesia and surgical procedures on the cognitive function of both young and aged mice. It will also explore the role and mechanisms of c-Fos expression in altering hippocampal neuron excitability and its relationship with perioperative neurocognitive disorders in mice.
Methods: In this study, we used a murine laparotomy model to assess cognitive behavioural changes in both young and aged mice at 1, 3, and 7 days post-surgery.
Physiol Behav
September 2025
Institute of Physical Education, Health and Leisure Studies, National Cheng Kung University, Taiwan; Department of Psychology, National Cheng Kung University, Taiwan. Electronic address:
This study investigated the effects of moderate-intensity aerobic exercise (MIAE) and MIAE combined with isometric resistance exercise on a whole-body vibration (WBV) platform (MIAE+WBV) compared with the effects of no exercise (NEI) on neurocognitive and molecular indices in 71 sedentary, healthy postmenopausal women. Participants were randomly assigned to MIAE (n = 23), MIAE+WBV (n = 23), and NEI (n = 25) groups. Neurocognitive measures, including accuracy rate (AR), reaction time (RT), and electroencephalogram-based event-related potentials (P2, N2, and P3 components) during the Stroop task, in addition to serum levels of insulin-like growth factor 1 (IGF-1), norepinephrine (NE), osteocalcin (OC), carboxylated OC (cOC), and uncarboxylated OC (ucOC), were evaluated before and after the intervention.
View Article and Find Full Text PDFJ Neurosurg
September 2025
2Latin American Neurosurgical Collaborative for Excellence in Research, Ciudad de México, México.
Objective: Open resective surgery (ORS) has become the standard of care for focal drug-resistant epilepsy (DRE). However, minimally invasive surgical alternatives, such as laser interstitial thermal therapy (LITT), have also been shown to be safe and effective. A meta-analysis comparing both treatments is warranted to assess the benefits of each modality for focal DRE.
View Article and Find Full Text PDF