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Background: The desire to improve accuracy and safety and to favor minimally invasive techniques has given rise to spinal robotic surgery, which has seen a steady increase in utilization in the past 2 decades. However, spinal surgery encompasses a large spectrum of operative techniques, and robotic surgery currently remains confined to assistance with the trajectory of pedicle screw insertion, which has been shown to be accurate and safe based on class II and III evidence. The role of robotics in improving surgical outcomes in spinal pathologies is less clear, however.
Methods: This comprehensive review of the literature addresses the role of robotics in surgical outcomes in spinal pathologies with a focus on the various meta-analysis and prospective randomized trials published within the past 10 years in the field.
Results: It appears that robotic spinal surgery might be useful for increasing accuracy and safety in spinal instrumentation and allows for a reduction in surgical time and radiation exposure for the patient, medical staff, and operator.
Conclusion: Robotic assisted surgery may thus open the door to minimally invasive surgery with greater security and confidence. In addition, the use of robotics facilitates tireless repeated movements with higher precision compared with humans. Nevertheless, it is clear that further studies are now necessary to demonstrate the role of this modern tool in cost-effectiveness and in improving clinical outcomes, such as reoperation rates for screw malpositioning.
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http://dx.doi.org/10.1016/j.wneu.2020.05.132 | DOI Listing |
Philos Trans A Math Phys Eng Sci
September 2025
Interdisciplinary Centre for Mathematical Modelling and Department of Mathematical Sciences, Loughborough University, Loughborough LE11 3TU, UK.
Nature uses elongated shapes and filaments to build stable structures, generate motion and allow complex geometric interactions. In this review, we examine the role of biological filaments across different length scales. From the molecular scale, where cytoskeletal filaments provide a robust but dynamic cellular scaffolding, over the scale of cellular appendages like cilia and flagella, to the scale of filamentous microorganisms like cyanobacteria, among the most successful genera on Earth, and even to the scale of elongated animals like worms and snakes, whose motility modes inspire robotic analogues.
View Article and Find Full Text PDFProg Cardiovasc Dis
September 2025
Department of Cardiology, University of Texas Health Science Center, San Antonio, TX, USA.
Background: Cardiopulmonary resuscitation (CPR) is a vital intervention for managing cardiac arrest; however, enhancing survival rates remains a significant challenge. Recent advancements highlight the importance of integrating artificial intelligence (AI) to overcome existing limitations in prediction, intervention, and post-resuscitation care.
Methods: A thorough review of contemporary literature regarding AI applications in CPR was undertaken, explicitly examining its role in the early prediction of cardiac arrest, optimization of CPR quality, and enhancement of post-arrest outcomes.
World J Urol
September 2025
Uro-Oncology Program, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Purpose: We aimed to evaluate the impact of day- and night-time pad wetness on 2yrs-QoL after Radical Cystectomy (RC) with Orthotopic Neobladder (ON) from a Randomized Controlled Trial (RCT) aimed at comparing open RC (ORC) and Robot-Assisted RC (RARC) with intracorporeal (i) ON.
Methods: Between January 2018 and September 2020, 116 patients were enrolled. Data from self-assessed questionnaires (EORTC-QLQ-C30 and QLQ-BLM30) were collected.
Epigenomics
September 2025
Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Aims: Psychological resilience refers to an individual's capacity to adapt to adverse events. MicroRNAs (miRNAs) play a crucial role in regulating post-transcriptional processes, while small extracellular vesicles (sEVs) act as transport vehicles. This study aimed to employ genome-wide profiling to identify and validate differences in the expression of resilience-associated sEV-miRNAs between low resilience (LR) and high resilience (HR) in young adults.
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