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Article Abstract
Unlabelled: Previous studies have recommended synovial fluid cell count thresholds of 50,000 cells/mm to diagnose septic arthritis; however, data to support this are limited. It is also unknown if this value is valid in immunosuppressed patients.
Methods: We retrospectively reviewed 33 immunosuppressed patients treated at our institution from 2008 to 2018. We compared culture-positive patients with culture-negative patients.
Results: We found no statistically significant differences in synovial fluid cell count, percent synovial fluid neutrophils, erythrocyte sedimentation rate, or C-reactive protein between the groups (all = 0.081). The median synovial fluid cell count in the culture-positive cohort was 29,000 cells/mm, with only 31.2% having >50,000 cells/mm.
Conclusion: Traditional synovial fluid cell thresholds are not a reliable method of diagnosing septic arthritis in immunosuppressed patients.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209792 | PMC |
| http://dx.doi.org/10.5435/JAAOSGlobal-D-20-00007 | DOI Listing |
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