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Safeguarding is rapidly rising up the international development agenda, yet literature on safeguarding in related research is limited. This paper shares processes and practice relating to safeguarding within an international research consortium (the ARISE hub, known as ARISE). ARISE aims to enhance accountability and improve the health and well-being of marginalised people living and working in informal urban spaces in low-income and middle-income countries (Bangladesh, India, Kenya and Sierra Leone). Our manuscript is divided into three key sections. We start by discussing the importance of safeguarding in global health research and consider how thinking about vulnerability as a relational concept (shaped by unequal power relations and structural violence) can help locate fluid and context specific safeguarding risks within broader social systems. We then discuss the different steps undertaken in ARISE to develop a shared approach to safeguarding: sharing institutional guidelines and practice; facilitating a participatory process to agree a working definition of safeguarding and joint understandings of vulnerabilities, risks and mitigation strategies and share experiences; developing action plans for safeguarding. This is followed by reflection on our key learnings including how safeguarding, ethics and health and safety concerns overlap; the challenges of referral and support for safeguarding concerns within frequently underserved informal urban spaces; and the importance of reflective practice and critical thinking about power, judgement and positionality and the ownership of the global narrative surrounding safeguarding. We finish by situating our learning within debates on decolonising science and argue for the importance of an iterative, ongoing learning journey that is critical, reflective and inclusive of vulnerable people.
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http://dx.doi.org/10.1136/bmjgh-2019-002253 | DOI Listing |
Cureus
August 2025
Orthopaedic Surgery, Sarah Bush Lincoln Bonutti Clinic, Effingham, USA.
Healthcare-associated infections (HAIs) continue to pose major risks to pediatric and neonatal patients, whose immature immune systems and unique vulnerabilities demand tailored infection prevention strategies. Traditional methods, including chemical disinfectants, procedural protocols, and physical hygiene measures, have contributed to reductions in HAIs but remain limited by human error, environmental toxicity, and the rise of antimicrobial resistance. Advances in disinfection technologies, particularly ultraviolet-C (UV-C) systems, offer promising new avenues for safer, more effective pathogen control.
View Article and Find Full Text PDFVet World
July 2025
Department of Geography, University College London, United Kingdom.
Background And Aim: Hospital effluents are a major source of environmental contaminants, harboring pathogenic bacteria, toxic trace metals, and high organic loads. This study aimed to evaluate the bacteriological and physicochemical profiles of wastewater discharged from three coastal hospitals in Oran, Algeria, and to assess the associated public and livestock health risks under the One Health approach.
Materials And Methods: A cross-sectional study was conducted from January 2023 to February 2024, involving monthly sampling at three hospitals and one drainage collector.
Alpha Psychiatry
August 2025
Experimental Research Center of Medical and Psychological Science, School of Psychology, Third Military Medical University, 400038 Chongqing, China.
Objective: To tailor culturally sensitive interventional strategies for safeguarding adolescents' mental health, this study investigated the role of perceived parental involvement in predicting depressive symptoms among Chinese adolescents, considering family socioeconomic status (SES).
Methods: A cluster convenience sampling method recruited 21,818 participants from 48 middle schools across 29 provinces in China. The perceived parental involvement (PPI) Scale and the Chinese version of the center for epidemiologic studies depression scale (CES-D) assessed parental involvement and depressive symptoms, respectively.
Diabetes Obes Metab
September 2025
Department of Pharmacology, Kagawa University, Kagawa, Japan.
Aim: Sodium-glucose cotransporter 2 (SGLT2) inhibitors consistently demonstrate renal protection against progressive kidney disease. We hypothesised that SGLT2 inhibition reduces blood glucose levels in peri-proximal tubular capillaries by limiting reabsorption from the tubular filtrate, thereby safeguarding the renal microvasculature from hyperglycaemic stress.
Materials And Methods: In anaesthetised streptozotocin-induced type 1 and Otsuka-Long Evans fatty (OLETF) type 2 diabetic rats, we measured the arterial-to-renal venous glucose ratio (RV/A) to evaluate the effects of canagliflozin, a SGLT2 inhibitor.
Contact Dermatitis
September 2025
Department of Chemical Engineering, School of Engineering, Monash University Malaysia, Bandar Sunway, Selangor Darul Ehsan, Malaysia.
Extended glove usage is crucial in various occupational settings to safeguard workers and maintain hygiene standards. However, prolonged wear creates an occlusive environment that disrupts normal skin evaporation, leading to temporary overhydration. This reversal of the diffusion gradient facilitates the penetration of residual soaps and alcohol from hand hygiene practices, which can deplete skin moisture and cause irritation.
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