Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Recent development of visible-light optical coherence tomography (vis-OCT) has introduced new applications for noninvasive spectroscopic imaging. However, the measured spectra may be altered by spectrally dependent roll-off (SDR). We formulated a mathematical model for SDR that accounted for nonuniform wavenumber spacing, optical aberrations, and misalignments in the spectrometer. We simulated SDR based on this model and found strong agreement with measurements from a vis-OCT system. We verified that SDR altered spectroscopic measurements of fully oxygenated blood. We corrected these alterations by normalizing each spectrally dependent A-line by the measured SDR of the spectrometer. Our investigations of SDR are critical for informing OCT spectrometer design, alignment, and spectroscopic measurements.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194246 | PMC |
| http://dx.doi.org/10.1364/OL.389240 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Individualized Frequency-Dependent Stimulation to the Anterior Nucleus of the Thalamus May Improve Antiepileptic Effects in Patients With Focal Epilepsy.
CNS Neurosci Ther
September 2025
Department of Functional Neurosurgery, Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Aim: A total of 30% of individuals with epilepsy are resistant to drug treatment. Deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) shows promise for treating drug-resistant epilepsy (DRE), but further research is needed to optimize DBS parameters, including stimulation frequency. This study aimed to reveal the optimal frequency for ANT-DBS by testing the real-time effects of various stimulation frequencies on the ANT among patients undergoing stereoelectroencephalography (SEEG) electrode implantation.
View Article and Find Full Text PDFSource-specific insights into photochemical and microbial degradation of dissolved organic matter in coastal environments.
Mar Environ Res
September 2025
Shandong Key Laboratory of Coastal Environmental Processes, Yantai, Shandong, 264003, China.
Coastal zones are critical for the biogeochemical cycling of dissolved organic matter (DOM) in marine ecosystems, yet the relative importance of photochemical and microbial degradation in DOM transformation remains poorly understood due to complex hydrodynamics, diverse sources, and human activities. Through 14-day laboratory incubations, we investigated DOM transformation mechanisms from three common marine coastal space uses: port, mariculture and inshore areas adjacent to Yantai City. DOM characterization was performed using fluorescence excitation-emission matrix parallel factor (EEM-PARAFAC) and UV-Vis spectroscopic indices.
View Article and Find Full Text PDFVisible Light Switching of -Functionalized Azo Phthalimides with Tunable -Isomer Stability.
J Org Chem
September 2025
Department of Organic Chemistry, University of Chemical Technology and Metallurgy, 8 St. Kliment Ohridski blvd, Sofia 1756, Bulgaria.
Herein, a novel class of azo photoswitches based on a phthalimide with an azo bond to the imide ring is presented, exhibiting reversible isomerization under a broad range of visible light irradiation from 405 to 530 nm. Structural variations with heteroaryl or aryl segments attached to the 3-phthalylazo unit exhibit distinct spectral features, such as red-shifted absorption, well-separated absorption bands, and tunable stability of the metastable isomer, ranging from seconds to days. They differ drastically in the half-life of -isomer stability, ranging from several seconds (-methylpyrrole) to days (-methylimidazole).
View Article and Find Full Text PDFDetection of a hybrid PrPfr state in the dark reversion of a bathy phytochrome indicates inter-dimer allostery.
Phys Chem Chem Phys
September 2025
Department of Chemistry - BMC, Biochemistry, Uppsala University, 75123 Uppsala, Sweden.
Phytochromes are photosensor proteins found in plants, fungi, and bacteria. They photoswitch between red light absorbing (Pr) and far-red light absorbing (Pfr) states. Thermal reversion in the dark, however, is an equally important factor in controlling their signaling levels.
View Article and Find Full Text PDFVocal tract contribution to vocal intensity: Interaction between vocal fold adduction, formant tuning, and fundamental frequency.
J Acoust Soc Am
September 2025
Department of Head and Neck Surgery, University of California, Los Angeles, 31-24 Rehab Center, 1000 Veteran Avenue, Los Angeles, California 90095-1794, USA.
The goal of this study was to understand the interaction between the voice source spectral shape, formant tuning, and fundamental frequency in determining the vocal tract contribution to vocal intensity. Computational voice simulations were performed with parametric variations in both vocal fold and vocal tract configurations. The vocal tract contribution to vocal intensity was quantified as the difference in the A-weighted sound pressure level between the radiated sound pressure and the sound pressure at the glottis.
View Article and Find Full Text PDF