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2,4,6-Trinitrophenol (TNP) has absorbed much concerns because of its toxic effect and threat on the environment, which results from the fact that it is an important and universal reagent widely utilized for manufacturing many products. It is of great necessity to explore facile and efficient methods for monitoring TNP. In present study, carbon dots (CDs), a new carbonaceous nanomaterial with strong fluorescence, was applied to build a novel sensor for highly sensitive and selective detection of TNP. In the sensing procedure, the fluorescence intensity of as-prepared CDs was diminished with the presence of TNP due to inner filter effect (IFE) quenching mechanism. The sensitivity of the fluorescent sensor was very high with limit of detection down to 5.37 ng mL. This fluorescent sensor was evaluated and excellent spiked recoveries were gained, which demonstrated that the developed sensor would be a robust tool for environmental applications.
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http://dx.doi.org/10.1016/j.scitotenv.2020.137680 | DOI Listing |
Talanta
September 2025
Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Viet Nam. Electronic address:
Food spoilage poses a global challenge with far-reaching consequences for public health, economic stability, and environmental sustainability. Conventional analytical methods for spoilage detection though accurate are often cost-prohibitive, labor-intensive, and unsuitable for real-time or field-based monitoring. Microfluidic paper-based analytical devices (μPADs) have emerged as a transformative technology offering rapid, portable, and cost-effective solutions for food quality assessment.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
September 2025
Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun 130122, China. Electronic address:
To achieve ultrasensitive and real-time detection of the H1N1 influenza virus, this study designed a nucleic acid-free fluorescent biosensor based on 3D spherical DNA nanostructure and CRISPR/Cas12a (3D-SDNC). The biosensor constructs a rigid 3D nano-framework via self-assembly of six oligonucleotide chains, with H1N1-specific nucleic acid aptamers and Cas12a activator strands strategically positioned at multi-spined vertices for precise spatial coupling between viral recognition and signal transduction. Upon aptamer-virus binding, the induced conformational change liberates the activator strand, thereby activating the trans-cleavage activity of the Cas12a/crRNA complex to efficiently cleave the HEX/BHQ1 double-labeled fluorescent probe and initiate cascade signal amplification.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
College of Chemistry and Chemical Engineering, Instrumental Analysis Center of Qingdao University, Qingdao Application Technology Innovation Center of Photoelectric Biosensing for Clinical Diagnosis and Treatment, Shandong Sino-Japanese Center for Collaborative Research of Carbon Nanomaterials, Qing
Silk fibroin (SF)-based flexible electronic/photonic materials have gained great attention in wearable devices and soft sensors. However, it remains challenging to understand the molecular interaction mechanisms and subsequently fabricate SF-based flexible materials that exhibit fluorescence, humidity sensitivity, and conductivity properties. In this study, by incorporating lanthanide europium ion (Eu), the design and fabrication of a flexible, fluorescent, and conductive SF membrane was proposed.
View Article and Find Full Text PDFFront Pharmacol
August 2025
Shenzhen Institute for drug Control, Shenzhen, China.
Introduction: The procedural complexity and time-consuming of conventional pesticide residue detection methods in traditional Chinese medicines (TCMs) significantly impeded their application in modern systems. To address this, this study presented an innovative dual-mode sensor driven by Cu/Cu redox-cycling, which achieved efficient signal transduction from enzyme inhibition to optical response for rapid acetylcholinesterase (AChE) activity and organophosphorus pesticide (OP) residue detection.
Methods: The AB-Cu NPs sensor, a dynamic redox-responsive system, was constructed via coordination-driven assembly of Azo-Bodipy 685 (AB 685) and Cu.