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Purpose: To firstly improve the attainable image SNR of F and H C F lung imaging at 1.5 tesla using an 8-element transmit/receive (Tx/Rx) flexible vest array combined with a 6-element Rx-only array, and to secondly evaluate microelectromechanical systems for switching the array elements between the 2 resonant frequencies.
Methods: The Tx efficiency and homogeneity of the 8-element array were measured and simulated for H imaging in a cylindrical phantom and then evaluated for in vivo F/ H imaging. The added improvement provided by the 6-element Rx-only array was quantified through simulation and measurement and compared to the ultimate SNR. It was verified through the measurement of isolation that microelectromechanical systems switches provided broadband isolation of Tx/Rx circuitry such that the F tuned Tx/Rx array could be effectively used for both F and H nuclei.
Results: For H imaging, the measured Tx efficiency/homogeneity (mean ± percent SD; ) was comparable to that simulated ( ). The 6 additional Rx-only loops increased the mean Rx sensitivity when compared to the 8-element array by a factor of 1.41× and 1.45× in simulation and measurement, respectively. In regions central to the thorax, the simulated SNR of the 14-element array achieves ≥70% of the ultimate SNR when including noise from the matching circuits and preamplifiers. A measured microelectromechanical systems switching speed of 12 µs and added minimum 22 dB of isolation between Tx and Rx were sufficient for Tx/Rx switching in this application.
Conclusion: The described single-tuned array driven at F and H, utilizing microelectromechanical systems technology, provides excellent results for F and H dual-nuclear lung ventilation imaging.
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http://dx.doi.org/10.1002/mrm.28260 | DOI Listing |
Sci Adv
September 2025
State Key Laboratory for Manufacturing System Engineering, State Industry-Education Integration Center for Medical Innovations, International Joint Laboratory for Micro/Nano Manufacturing and Measurement Technologies, Shaanxi Innovation Center for Special Sensing and Testing Technology in Extreme En
Continuous monitoring of cardiovascular vital signs can reduce the incidence and mortality of cardiovascular diseases, yet cannot be implemented by current technologies because of device bulkiness and rigidity. Here, we report self-adhesive and skin-conformal ultrasonic transducer arrays that enable wearable monitoring of multiple hemodynamic parameters without interfering with daily activities. A skin-adaptive focused ultrasound method with rational array design is proposed to implement measurement under wide ranges of skin curvatures and depths with improved sensing performances.
View Article and Find Full Text PDFPhys Chem Chem Phys
September 2025
Key Laboratory of Special Functional Materials Manufacturing Processes and Equipment Ministry of Education, College of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing, 100029, China.
The development of environmentally friendly solid lubricants with exceptional wear resistance is imperative to address the escalating environmental concerns and performance limitations of conventional lubricants in demanding tribological applications. This study systematically investigated the wear resistance of hydroxypropyl methylcellulose (HPMC)/tungsten disulfide (WS)/graphene composites under normal applied loads (2 and 4 N) and varying solid lubricant contents (stoichiometric ratios of 0.2 referred to as CWG-0.
View Article and Find Full Text PDFNanophotonics
August 2025
Departament d'Enginyeria Electrònica i Biomèdica, Universitat de Barcelona, 08028 Barcelona, Spain.
One-dimensional photonic crystal (1D-PhC) pillar cavities allow transducing mechanical pillar vibrations to the optical domain, thereby relaxing the requirements typically associated with mechanical motion detection. In this study, we integrate these geometries into a silicon-on-insulator photonics platform and explore their optical and mechanical properties. The 1D-PhC structures consist of a linear array of high aspect ratio nanopillars with nanometer-sized diameters, designed to enhance the interaction between transverse-magnetic (TM) polarized optical fields and mechanical vibrations and to minimize optical leaking to the substrate.
View Article and Find Full Text PDFSci Rep
August 2025
Institute of Communications Engineering, University of Rostock, Albert-Einstein-Str. 26, Rostock, 18059, Germany.
In Parkinson's disease (PD), continuous sensor-based evaluation of motor symptom severity, e.g., using accelerometry, has become an emerging field of interest in clinical research.
View Article and Find Full Text PDFPharmaceuticals (Basel)
August 2025
Chemistry Centre of University of Minho (CQ-UM), Campus de Gualtar, 4710-057 Braga, Portugal.
Cancer is one of the deadliest diseases worldwide. Despite the existing treatments, the adverse side effects and the increasing drug resistance to the current therapies lead to a reduced quality of life for patients and poor prognosis. The pyrimido[5,4-]pyrimidine compound () was identified as a promising new anticancer drug due to its potent activity against colorectal and triple-negative breast cancers; however it showed poor aqueous solubility and safety profile.
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