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Skull base tumors arising from the middle cranial fossa and invading of the infratemporal fossa (ITF) and middle cranial fossa are challenging for neurosurgeons, because of complex anatomy and critical neurovascular structure involvement. The first pioneering ITF approaches resulted in invasive procedures and carried a high rate of surgical morbidity. However, the acquisition of deep anatomical knowledge, and the development operative skills and reconstruction techniques allowed surgeons to achieve total or near total resection of many ITF lesions with a low morbidity rate. In Video 1 we illustrate our technique for the anterior ITF approach for the surgical treatment of a middle cranial fossa meningioma invading the ITF. This surgical video describes the anterior ITF approach in 2 steps. First, a standard extradural middle fossa approach subtemporal approach is performed on a cadaveric specimen, illustrating the anterior extension to the cavernous sinus. Second, the anterior ITF approach is performed for the surgical treatment of a temporal lobe meningioma with extension to the anterior ITF. This technique provides a minimally invasive approach for treating middle fossa lesions with anterior ITF extension.
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http://dx.doi.org/10.1016/j.wneu.2020.02.141 | DOI Listing |
World Neurosurg
September 2025
Microsurgical Neuroanatomy Laboratory, Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpaşa, Istanbul, Turkey; Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpaşa, Istanbul, Turkey. Electronic address:
Introduction: The infratemporal fossa (ITF) represents a complex anatomical region of critical relevance in skull base surgery, particularly due to its involvement in the extension of neoplastic lesions. Surgical access to this region remains technically demanding. The orbitozygomatic (OZ) and transmandibular (TM) approaches offer distinct anatomical perspectives and operative corridors.
View Article and Find Full Text PDFBDJ Open
June 2025
Faculty of Dentistry, Van Lang University, Ho Chi Minh City, Vietnam.
Introduction: Zygomatic implants represent a reliable treatment modality for patients with severe maxillary bone resorption, eliminating the need for bone grafting and enabling immediate loading. This study utilized cone beam computed tomography (CBCT) to identify optimal zygomatic bone regions for implant placement by assessing bone-implant contact (BIC) while minimizing intrusion risks into the infratemporal fossa (ITF). Additionally, differences in zygomatic characteristics between males and females were investigated to address the limited evidence regarding the influence of biological sex on BIC and implant stability.
View Article and Find Full Text PDFCurr Oncol
February 2025
Department of Medical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai 400094, India.
Background: According to the 8th edition of the American Joint Committee on Cancer (AJCC), involvement of the masticator space and infratemporal fossa (ITF) in oral cancers indicates advanced disease (T4b), which is often considered unresectable. Previous studies have shown that the extent of ITF involvement influences management and outcomes. Therefore, to optimize management, T4b disease should be subclassified based on ITF involvement.
View Article and Find Full Text PDFJ Craniofac Surg
August 2025
Department of Neurosurgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University.
Objective: To investigate the feasibility and related anatomical structures of the infratemporal fossa (ITF) through minimally invasive endoscopic lateral approach, so as to provide anatomical data and basis for clinical surgery.
Methods: Six adult cadaveric heads were used to simulate the surgical dissection of the ITF through a minimally invasive endoscopic lateral approach, and the important vessels, nerves, and other structures in the surgical pathway and the surrounding adjacent relationships were observed, and relevant pictures were collected.
Results: The maxillary arteries of 6 cadaver specimens (12 sides) were located on the surface of the lateral pterygoid muscle in 9 cases, and between the upper and lower heads of the lateral pterygoid muscle in 3 cases, constant branches were the deep temporal artery, pterygoid artery, masseter artery, and buccal artery.
Int J Surg Case Rep
February 2025
Department of Otolaryngology Head and Neck Surgery, King Fahad Specialist Hospital, Dammam, Saudi Arabia. Electronic address:
Introduction: The infratemporal fossa (ITF) is considered an uncommon location for giant cell granuloma (GCG), a rare benign disease that is frequently detected in the maxilla and mandible.
Presentation Of Case: A 47-year-old male presented with right-sided hearing loss, tinnitus, and jaw claudication. Radiological imaging confirmed the presence of a mass in the ITF accompanied by bone erosion.