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Snapshot multispectral image (MSI) sensors have been proposed as a key enabler for a plethora of multispectral imaging applications, from diagnostic medical imaging to remote sensing. With each application requiring a different set, and number, of spectral bands, the absence of a scalable, cost-effective manufacturing solution for custom multispectral filter arrays (MSFAs) has prevented widespread MSI adoption. Despite recent nanophotonic-based efforts, such as plasmonic or high-index metasurface arrays, large-area MSFA manufacturing still consists of many-layer dielectric (Fabry-Perot) stacks, requiring separate complex lithography steps for each spectral band and multiple material compositions for each. It is an expensive, cumbersome, and inflexible undertaking, but yields optimal optical performance. Here, we demonstrate a manufacturing process that enables cost-effective wafer-level fabrication of custom MSFAs in a single lithographic step, maintaining high efficiencies (∼75%) and narrow line widths (∼25 nm) across the visible to near-infrared. By merging grayscale (analog) lithography with metal-insulator-metal (MIM) Fabry-Perot cavities, whereby exposure dose controls cavity thickness, we demonstrate simplified fabrication of MSFAs up to -wavelength bands. The concept is first proven using low-volume electron beam lithography, followed by the demonstration of large-volume UV mask-based photolithography with MSFAs produced at the wafer level. Our framework provides an attractive alternative to conventional MSFA manufacture and metasurface-based spectral filters by reducing both fabrication complexity and cost of these intricate optical devices, while increasing customizability.
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http://dx.doi.org/10.1021/acsphotonics.9b01196 | DOI Listing |
Adv Healthc Mater
September 2025
Department of Biomedical Engineering, University of Delaware, Newark, DE, 19716, USA.
Organ-on-chip (OOC) technologies, also called microphysiological systems (MPS), offer dynamic microenvironments that improve upon static culture systems, yet widespread adoption has been hindered by fabrication complexity, reliance on polydimethylsiloxane (PDMS), and limited modularity. Here, a modular MPS platform is presented, designed for ease of use, reproducibility, and broad applicability. The system comprises layered elastomeric inserts for dual monolayer cell culture, which is clamped within a reusable acrylic cassette for perfusion studies.
View Article and Find Full Text PDFBMC Med Educ
September 2025
Department of Prosthodontics, University of Würzburg, Pleicherwall 2, 97070, Würzburg, Germany.
Background: Bridge preparation skills are a vital component of dental education and require specific techniques. This study aimed to develop and evaluate 3D printed teeth for use in defect-oriented bridge preparation and pre-prosthetic exercises in dental training, addressing the limited customization and lack of integrated workflows found in commercial typodont teeth. The null hypothesis stated that 3D printed teeth offered no advantage over established typodont training methods for bridge preparation.
View Article and Find Full Text PDFJ Prosthet Dent
September 2025
Associate Professor, Department of Dental Surgery, Faculty of Dental Surgery, University of Malta, Malta. Electronic address:
A digital workflow merging root submergence, immediate dental implant and definitive intermediate abutment placements, and custom healing abutment fabrication to enhance esthetic and biological outcomes in immediate implant procedures is described. The procedure involves a prosthetically driven plan on intraoral and cone beam computed tomography (CBCT) scans, digital planning using a specialized software program, the creation of a surgical guide, and the digital design of custom components. A 3-dimensionally (3D) printed healing abutment was produced by following specific protocols.
View Article and Find Full Text PDFPLoS One
September 2025
Sterile Processing Department, Sichuan GEM Flower Hospital, North Sichuan Medical College, Chengdu, China.
Background: Luminal instruments are characterized by their slender internal lumens, which make them particularly challenging to clean and dry. A common drying method used by Sterile Processing Department (SPD) technicians involves blowing high-pressure air into one end of the lumen to expel moisture. However, this process generates a significant amount of aerosols that may contain bacteria, viruses, and other microorganisms.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Archaeology and Heritage Studies, School of Culture and Society, Aarhus University, Højbjerg, Denmark.
This article presents a multiproxy investigation of metal samples obtained from 48 Nuragic figurines (so-called bronzetti) and three copper bun ingots. These objects originate from three prominent Sardinian sanctuaries and one unidentified site, dating to the late Nuragic period of the early first millennium BCE. The dataset significantly expands the existing scientific database and unwraps the complex fabrication biographies of the figurines from ore to finished object.
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