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http://dx.doi.org/10.1093/ajcn/nqz253 | DOI Listing |
PLoS One
September 2025
Department of Pathology, Boston Children's Hospital, Harvard School of Medicine, Boston, Massachusetts, United States of America.
The Sudden Infant Death Syndrome (SIDS) is a major global health problem, with increased risk among socioeconomically disadvantaged populations. We propose SIDS, or a subset, is due to a defect in the brainstem serotonin system mediating cardiorespiratory integration and arousal. This defect impinges on homeostasis during a critical developmental period in infancy, especially in populations experiencing maternal and infantile stress, resulting in sleep-related sudden death.
View Article and Find Full Text PDFInt J Surg
September 2025
Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Background: Phrenic nerve injury during mediastinal tumor resection can lead to significant postoperative diaphragmatic dysfunction. Current intraoperative protection techniques are imprecise and lack real-time feedback. We aimed to develop and validate a quantifiable, multimodal neuroprotective strategy.
View Article and Find Full Text PDFMed Int (Lond)
August 2025
Department of Epidemiology, School of Public Health, Zhengzhou University, Zhengzhou, Henan 450001, P.R. China.
Punicalagin, a polyphenolic compound extracted from pomegranate peel, has received increasing attention in recent years due to its antibacterial and antiviral properties. Punicalagin is capable of inhibiting bacterial growth at sub-inhibitory concentrations by affecting cell membrane formation, disrupting membrane integrity, altering cell permeability, affecting efflux pumps, interfering with quorum sensing and influencing virulence factors. Additionally, punicalagin inhibits viruses by modulating enzyme activity, interacting with viral surface proteins, affecting gene expression, blocking viral attachment, disrupting virus receptor interaction and inhibiting viral replication.
View Article and Find Full Text PDFMethodsX
December 2025
Department of Earth and Environmental Science, University of Waterloo, Waterloo, ON, Canada.
Human factors are central to aviation safety, with pilot cognitive states such as workload, stress, and situation awareness playing important roles in flight performance and safety. Although flight simulators are widely used for training and scientific research, they often lack the ecological validity needed to replicate pilot cognitive states from real flights. To address these limitations, a new in-flight data collection methodology for general aviation using a Cessna 172 aircraft, which is one of the most widely used aircraft for pilot training, is presented.
View Article and Find Full Text PDFScand J Surg
September 2025
Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Scientific integrity relies on reproducibility. Reproducible scientific results are essential for advancing clinical practice and improving patient outcomes. However, despite the importance, reproducibility issues are widespread, often arising from inadequate methodologies and a lack of expertise in research design.
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