98%
921
2 minutes
20
The stagnant region often appears in front of the tool cutting edge, which is caused by mechanical inlay and excessive pressing in plastic metal cutting with large negative rake angle tools at a low speed. It results in the change of the effective negative rake angle which can affect the flow characteristics of material, the quality of machined surface and the abrasion loss of cutting tools. However, the critical negative rake angle model based on the existence of the stagnant region has not been reported yet. Therefore, in order to investigate the critical negative rake angle value considering the stagnant region, a critical negative rake angle model based on the principle of minimum required energy is established, and the correctness of the theoretical model is verified by orthogonal cutting experiments. At the same time, the influence of the critical value of the large negative rake angle tool on the machined surface quality is studied through different cutting experiments. These experimental results show that the deviations of both experimental and theoretical critical negative rake angle are less than 5% during the orthogonally cutting of the aluminium (AL1060) and copper (T2) materials by the negative rake angle tool. Meanwhile, the critical negative rake angle is related to the adhesive friction coefficient of tool-workpiece contact surface. The analysis of friction characteristics shows that the deviation values of both theoretical and experimental critical negative rake angle are proportional to the coefficient of adhesive friction and the thickness of the stagnant region. Critical negative rake angle has a significant effect on roughness and residual stress of the machined surface.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453752 | PMC |
http://dx.doi.org/10.1177/0036850419878065 | DOI Listing |
Khirurgiia (Mosk)
August 2025
Tatarstan Regional Clinical Cancer Center, Kazan, Russia.
Objective: To study the immediate and long-term results of multivisceral surgeries with pancreaticoduodenectomy for gastric cancer.
Material And Methods: The 1 group included 24 patients who underwent multivisceral surgeries with pancreaticoduodenectomy for gastric cancer with pancreatic head and/or duodenum invasion. The 2 group included 60 patients with gastric cancer who underwent partial resection of the pancreatic head and/or duodenum rather pancreaticoduodenectomy.
Head Neck Pathol
August 2025
Division of Oral and Maxillofacial Pathology, School of Dentistry, University of Minnesota, 515 Delaware Street SE #!6-116B, Minneapolis, MN, 55455, USA.
Oral Kaposi sarcoma is a slowly progressing, HHV-8 related angioproliferative disorder strongly associated with immunosuppression. Regression can occur with treatment. We present a 49-year-old HIV-seronegative Caucasian male individual with two rapidly enlarging OKS lesions that spontaneously regressed and completely resolved without treatment after a few months.
View Article and Find Full Text PDFBreast cancer (BC) with triple-negative molecular profile is characterized by special and rather serious problems in terms of clinical management of patients compared to other types. On the one hand this is due to the fact that tumors with such a status often do not respond to routine targeted therapy and only a minimal number of drugs are currently available for their treatment. On the other hand, cases of triple-negative BC (TNBC) are often diagnosed against the background of an extensive metastatic process, in which confirmation of the metastases histogenesis to breast tissue is a difficult task due to the low sensitivity of such carcinomas to specific organ markers.
View Article and Find Full Text PDFArkh Patol
June 2025
Lomonosov Moscow State University, Moscow, Russia.
Objective: To evaluate the degree of tumor budding by three methods in gastric cancer and to study its relationship with clinical and morphological characteristics and its impact on overall survival. Choose the best way to determine the tumor budding in gastric cancer.
Material And Methods: In the surgical material from 172 patients with verified gastric cancer of the tubular histological subtype, tumor budding was identified and counted using three methods: H.
Arkh Patol
April 2025
Novosibirsk State Medical University, Novosibirsk, Russia.
Unlabelled: The development of drugs with the ability to increase differentiation and reduce tumor malignancy is one of the promising directions in the treatment of breast cancer (BC). As such, Human Leukemia Differentiation Factor (HLDF), a protein consisting of 54 amino acids and contributing to an increase in the degree of differentiation of invasive ductal breast carcinoma cells, can be used. The key disadvantage of the full-size HLDF is its rapid biodegradation.
View Article and Find Full Text PDF