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Background: Preoperatively identifying patients who will require discharge to extended care facilities (ECFs) after major cancer surgery is valuable. This study compares existing models and derives a simple, preoperative tool for predicting discharge destination after major oncologic gastrointestinal surgery.
Methods: The American College of Surgeon National Surgical Quality Improvement datasets were used to evaluate existing risk stratification and frailty assessment tools between the years 2011 and 2015. A novel tool for predicting discharge to ECF was developed in the 2011-2015 dataset and subsequently validated in the 2016 dataset.
Results: Major resections were analyzed for 61 683 malignancies: 6.9% esophagus, 5.3% stomach, 20.0% liver, 21.0% pancreas, and 46.8% colon/rectum. The overall ECF discharge rate was 9.1%. The American Society of Anesthesiologist score, 11-point modified frailty index (mFI), and 5-point abbreviated modified frailty index (amFI) demonstrated only moderate discrimination in predicting ECF discharge (c-statistic: 0.63-0.65). In contrast, our weighted cancer cancer abbreviated modified frailty index (camFI) score demonstrated improved discrimination with c-statistic of 0.73. The camFI displayed >90% negative predictive value for ECF discharge at every operative site.
Conclusion: The camFI is a simple tool that can be used preoperatively to counsel patients on their risk of ECF discharge, and to identify patients with the least need for ECF discharge after major oncologic gastrointestinal surgery.
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http://dx.doi.org/10.1002/jso.25767 | DOI Listing |
Cureus
May 2025
Emergency Medicine, Penn State College of Medicine, Hershey, USA.
Introduction Sepsis is defined as life-threatening organ dysfunction due to a dysregulated host response to infection, and is one of the leading causes of morbidity and mortality globally. This study was undertaken to investigate the role of healthcare encounters and diagnostic test results in the 30 days preceding a sepsis diagnosis. Methods In this single-center retrospective chart review, eligible subjects were 18 years of age and older who presented to the ED and were diagnosed with either sepsis or septic shock in the ED or inpatient setting between January 2020 and September 2023.
View Article and Find Full Text PDFJ Clin Endocrinol Metab
May 2025
Division of Emergency Medicine and High Dependency Unit, Department of Medical Sciences, University Hospital "Città della Salute e della Scienza di Torino", Turin, Italy.
Context: The role of copeptin in assessing hyponatremic patients at emergency department (ED) admission remains debated.
Objective: To assess copeptin's effectiveness in evaluating extracellular fluid (ECF) volume and its predictive value in hyponatremic adults admitted to the medical ED.
Design: Report from the IPSO-URG, a prospective cohort study with recruitment from June 2018 to August 2019 and 6-month follow-up.
BMC Musculoskelet Disord
February 2025
Department of Biomedical and Diagnostic Sciences. Preventive Medicine and Public Health, Faculty of Medicine, Universidad de Salamanca. Campus Miguel de Unamuno, Avda. Alfonso X El Sabio S/N, 37007, Salamanca, Spain.
Background: Benefits of partial weight bearing (PWB) in operated extracapsular hip fractures (ECF) have not been proved. We have assessed influence of PWB on long-term survival and the final mobility achieved, dependence and mortality-related factors.
Methods: Retrospective cohort study of osteoporotic ECF in ≥ 65-year-old patients who underwent surgery with trochanteric Gamma3 nails in 2014 (n = 218), followed in the long-term (consolidation or stabilisation).
Vet Med Sci
March 2025
Department of Equine Clinical Sciences, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Neston, UK.
Background: Predicting outcome in horses presenting with colic remains challenging.
Objectives: To test whether arterial blood samples in horses admitted for colic predict outcome to hospital discharge for different colic types.
Methods: Arterial blood samples collected on admission from 358 horses undergoing medical or surgical management of colic were evaluated for pH, PaO, PaCO, Na, K, iCa, Cl, HCO (P), HCO (P, set), Base (B), Base (ecf) and anion gap.
Nutr Clin Pract
February 2025
Department of Surgery, Denver Health Medical Center, University of Colorado, Denver, Colorado, USA.
Nutrition plays an integral role in the management of patients with enterocutaneous fistula (ECF), but practice guidelines are often vague because of limited evidence. As a result, clinicians must rely on expert consensus and sound nutrition principles to guide practice. The initial phase of ECF management involves recognition (eg, fistula location and quantifying output) and stabilization (eg, source control and fluid and electrolyte balance).
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